Endocannabinoid system: chemical characteristics and biological activity

B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023‏ - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

Cannabidiol (CBD) in cancer management

K O'Brien - Cancers, 2022‏ - mdpi.com
Simple Summary Cannabidiol (CBD) is one of the main constituents of the plant Cannabis
sativa. Surveys suggest that medicinal cannabis is popular amongst people diagnosed with …

[HTML][HTML] Maternal cannabis use during lactation and potential effects on human milk composition and production: a narrative review

I Castro-Navarro, MA McGuire, JE Williams… - Advances in …, 2024‏ - Elsevier
Cannabis use has increased sharply in the last 20 y among adults, including reproductive-
aged women. Its recent widespread legalization is associated with a decrease in risk …

Phytocannabinoids and cannabis-based products as alternative pharmacotherapy in neurodegenerative diseases: From hypothesis to clinical practice

Y Paes-Colli, AFL Aguiar, AR Isaac… - Frontiers in cellular …, 2022‏ - frontiersin.org
Historically, Cannabis is one of the first plants to be domesticated and used in medicine,
though only in the last years the amount of Cannabis-based products or medicines has …

A delightful trip along the pathway of cannabinoid and endocannabinoid chemistry and pharmacology

R Mechoulam - Annual Review of Pharmacology and Toxicology, 2023‏ - annualreviews.org
After a traumatic childhood in Europe during the Second World War, I found that scientific
research in Israel was a pleasure beyond my expectations. Over the last 65 year, I have …

Non-psychoactive cannabinoid modulation of nociception and inflammation associated with a rat model of pulpitis

EY Laks, H Li, SJ Ward - Biomolecules, 2023‏ - mdpi.com
Despite advancements in dental pain management, one of the most common reasons for
emergency dental care is orofacial pain. Our study aimed to determine the effects of non …

Fish oil supplementation during pregnancy decreases liver endocannabinoid system and lipogenic markers in newborn rats exposed to maternal high-fat diet

LB Fassarella, JGO Neto, J Woyames… - European Journal of …, 2024‏ - Springer
Purpose Maternal high-fat diet (HF) programs obesity, metabolic dysfunction-associated
steatotic liver disease (MASLD), hypertriglyceridemia, and hyperglycemia associated with …

The importance of medical cannabis for solving the problem of providing analgesia to palliative patients in Ukraine

ВМ Лехан - Експериментальна і клінічна медицина, 2024‏ - ecm.knmu.edu.ua
One of the ways to solve the problem of pain relief for palliative patients in Ukraine is to
expand the arsenal of painkillers through the use of medical cannabis. In many palliative …

[HTML][HTML] Long-Term Treatment with Cannabidiol-Enriched Cannabis Extract Induces Synaptic Changes in the Adolescent Rat Hippocampus

AFL Aguiar, RMP Campos, AR Isaac… - International Journal of …, 2023‏ - mdpi.com
The endocannabinoid system (eCS) is widely distributed in mammalian tissues and it is
classically formed by cannabinoid receptors, endogenous bioactive lipids and its synthesis …

Cannabis constituents for chronic neuropathic pain; reconciling the clinical and animal evidence

E Sokolaj, N Assareh, K Anderson… - Journal of …, 2024‏ - Wiley Online Library
Chronic neuropathic pain is a debilitating pain syndrome caused by damage to the nervous
system that is poorly served by current medications. Given these problems, clinical studies …