There is growing recognition of the importance of the design of the built environment in
supporting mental health. In this context, trauma-informed design has emerged as a new …

This study aimed to scrutinize existing evidence concerning the link between somatic
symptoms and nervous system activity. The goal was to pinpoint areas for effective …

The role of psychological factors in the pathophysiology and treatment of chronic visceral
pain in disorders of gut-brain interactions (DGBI) is increasingly appreciated. Placebo …

Panic disorder is a common psychiatric diagnosis characterized by acute, distressing
somatic symptoms that mimic medically-relevant symptoms. As a result, individuals with …

Inflammation could impact on the formation and persistence of interoceptive fear and
hypervigilance, with relevance to psychiatric disorders and chronic pain. To systematically …

Active avoidance (AA) is an adaptive response to potentially harmful situations while
maladapted avoidance that does not extinguish is one of the core symptoms of anxiety and …

The medial prefrontal cortex (mPFC) is required for learning associations that determine
whether animals approach or avoid potential threats in the environment. Dopaminergic (DA) …

The medial prefrontal cortex (mPFC) resolves approach-avoidance conflicts and mediates
15 associative processes required for learning to avoid threats. Dopamine (DA) projections …

The amygdala is a core structure of the limbic system in the brain. Anatomically, the
amygdaloid complex comprises~ 13 nuclei in the mid-temporal lobe. The amygdaloid …

Gemäß dem biopsychosozialen Krankheitsmodell spielen diverse psychosoziale Faktoren
eine zentrale Rolle bei der Entstehung, Pathophysiologie und Behandlung von Störungen …