The human leukocyte antigen (HLA) super-locus is a genomic region in the chromosomal
position 6p21 that encodes the six classical transplantation HLA genes and at least 132 …

The cytometric enumeration and characterization of antigen‐specific lymphocytes, as
introduced about 15 years ago, has contributed significantly to our understanding of …

Therapeutic options for autoimmune diseases typically consist of broad and targeted
immunosuppressive agents. However, sustained clinical benefit is rarely achieved, as the …

Abstract Development of disease-modifying therapies against Alzheimer's disease (AD)
requires biomarkers reflecting the diverse pathological pathways specific for AD. We …

Autoimmune diseases (ADs) showcase the intricate balance between the immune system's
protective functions and its potential for self-inflicted damage. These disorders arise from the …

T cell immunity is crucial for control of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection and has been studied widely on a quantitative level. However, the …

Natural killer (NK) cells have important functions in the innate immunity to tumors.
Recognition of tumor cells by NK cells is mediated by the interaction of activating and …

Angiogenesis, barriergenesis, and immune cell migration are all key physiological events
that are dependent on the functional characteristics of the vascular endothelium. The protein …

Asthma exacerbations are associated with significant childhood morbidity and mortality.
Recurrent asthma attacks contribute to progressive loss of lung function and can sometimes …

The MHC is a highly polymorphic genomic region that encodes the transplantation and
immune regulatory molecules. It receives special attention for genetic investigation because …