Emerging treatments and the clinical trial landscape for hidradenitis suppurativa part I: topical and systemic medical therapies
Hidradenitis suppurativa (HS) is an oftentimes debilitating condition that presents with
painful nodules, abscesses, and sinus tracts. This condition is challenging to treat, in part …
painful nodules, abscesses, and sinus tracts. This condition is challenging to treat, in part …
Biology of interleukin-17 and novel therapies for hidradenitis suppurativa
R Sabat, JE Gudjonsson, NC Brembilla… - Journal of Interferon & …, 2023 - liebertpub.com
Skin disorders affect∼ 40% of the human population. One of the most debilitating cutaneous
disorders is Hidradenitis suppurativa (HS), a noncommunicable chronic inflammatory …
disorders is Hidradenitis suppurativa (HS), a noncommunicable chronic inflammatory …
[HTML][HTML] Saharan dust induces the lung disease-related cytokines granulocyte–macrophage colony-stimulating factor and granulocyte colony-stimulating factor
Desert dust exposure is associated with adverse respiratory health effects. Desert dust is a
complex pollutant mixtures that includes respirable crystalline and amorphous particles …
complex pollutant mixtures that includes respirable crystalline and amorphous particles …
Transcriptomic Analysis of Hidradenitis Suppurativa: A Unique Molecular Signature with Broad Immune Activation
Hidradenitis suppurativa is a chronic inflammatory skin disease with limited treatment
options. The poorly understood pathogenesis hinders the development of effective …
options. The poorly understood pathogenesis hinders the development of effective …
Whole blood transcriptomics reveals granulocyte colony‐stimulating factor as a mediator of cardiopulmonary bypass‐induced systemic inflammatory response …
KR Martin, C Gamell, TY Tai, R Bonelli… - Clinical & …, 2024 - Wiley Online Library
Objectives Systemic inflammatory response syndrome (SIRS) is a frequent complication of
cardiopulmonary bypass (CPB). SIRS is associated with significant morbidity and mortality …
cardiopulmonary bypass (CPB). SIRS is associated with significant morbidity and mortality …
Inflammatory loop involving Staphylococcus aureus, IL-36γ, and cathepsin S drives immunity disorders in familial acne inversa keratinocytes
Y Zhang, W Jia, X Wang, Q Mao, L Luo, L Kong, Y Guo… - Heliyon, 2024 - cell.com
Acne inversa (AI) is an inflammatory skin disease associated with nicastrin (NCSTN)
mutations. Despite the dysregulated bacterial–host immune interactions being an essential …
mutations. Despite the dysregulated bacterial–host immune interactions being an essential …
Report of successful treatment of follicular occlusion triad with adalimumab and research progress on biologic therapy for follicular occlusion triad
R Jia, Q Diao, Y Wang - Journal of Dermatological treatment, 2024 - Taylor & Francis
Purpose: This article aims to present a case report of a patient with Follicular occlusion triad
(FOT) who achieved successful disease control with adalimumab combined with isotretinoin …
(FOT) who achieved successful disease control with adalimumab combined with isotretinoin …
Hope for a new therapy for hidradenitis suppurativa: blocking of granulocyte colony-stimulating factor receptor
K Wolk - British Journal of Dermatology, 2023 - academic.oup.com
There is little evidence on the optimal clinical and histological margins required to reduce
local recurrence in melanoma in situ (MIS.) Our aim was to identify the number of lesions on …
local recurrence in melanoma in situ (MIS.) Our aim was to identify the number of lesions on …
Microwave Energy for Managing Hidradenitis Suppurativa
N Bielecki, A Hoover - SKIN The Journal of Cutaneous …, 2024 - skin.dermsquared.com
Results: These five patient cases demonstrate how ME treatments can lead to a rapid
reduction in reported pain and erythema as well as clinical-assessed clearance of several …
reduction in reported pain and erythema as well as clinical-assessed clearance of several …