Mendelian randomization: concepts and scope
RC Richmond, GD Smith - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
Oxidative stress mitigation by antioxidants-an overview on their chemistry and influences on health status
The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …
Mitochondrial dysfunction and oxidative stress in heart disease
Beyond their role as a cellular powerhouse, mitochondria are emerging as integral players
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
in molecular signaling and cell fate determination through reactive oxygen species (ROS) …
Antioxidant and oxidative stress: a mutual interplay in age-related diseases
Aging is the progressive loss of organ and tissue function over time. Growing older is
positively linked to cognitive and biological degeneration such as physical frailty …
positively linked to cognitive and biological degeneration such as physical frailty …
Ageing, age-related diseases and oxidative stress: What to do next?
Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …
Using genetic data to strengthen causal inference in observational research
Causal inference is essential across the biomedical, behavioural and social sciences. By
progressing from confounded statistical associations to evidence of causal relationships …
progressing from confounded statistical associations to evidence of causal relationships …
[HTML][HTML] Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and …
Background High dietary intake or blood concentrations (as biomarkers of dietary intake) of
vitamin C, carotenoids, and vitamin E have been associated with reduced risk of …
vitamin C, carotenoids, and vitamin E have been associated with reduced risk of …
Антиоксиданты в комплексной терапии атеросклероза: pro et contra
ВЗ Ланкин, АК Тихазе, ЮН Беленков - Кардиология, 2004 - elibrary.ru
В обзоре литературы обсуждаются современные представления о роли
свободнорадикальных процессов в формировании окислительного стресса при …
свободнорадикальных процессов в формировании окислительного стресса при …
[HTML][HTML] Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies
abstract Mendelian randomization (MR) is an increasingly important tool for appraising
causality in observational epidemiology. The technique exploits the principle that genotypes …
causality in observational epidemiology. The technique exploits the principle that genotypes …
Coronary artery disease: from mechanism to clinical practice
C Shao, J Wang, J Tian, Y Tang - Coronary Artery Disease: Therapeutics …, 2020 - Springer
In most developed countries, coronary artery disease (CAD), mostly caused by
atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to …
atherosclerosis of coronary arteries, is one of the primary causes of death. From 1990s to …