Stem cell-laden hydrogel-based 3D bioprinting for bone and cartilage tissue engineering

Z Yang, P Yi, Z Liu, W Zhang, L Mei, C Feng… - … in bioengineering and …, 2022‏ - frontiersin.org
Tremendous advances in tissue engineering and regenerative medicine have revealed the
potential of fabricating biomaterials to solve the dilemma of bone and articular defects by …

Collagen hydrogel viscoelasticity regulates MSC chondrogenesis in a ROCK-dependent manner

D Huang, Y Li, Z Ma, H Lin, X Zhu, Y **ao, X Zhang - Science advances, 2023‏ - science.org
Mesenchymal stem cell (MSC) chondrogenesis in three-dimensional (3D) culture involves
dynamic changes in cytoskeleton architecture during mesenchymal condensation before …

Collagen‐Based Hydrogels for Cartilage Regeneration

L Sun, Y Xu, Y Han, J Cui, Z **g, D Li, J Liu… - Orthopaedic …, 2023‏ - Wiley Online Library
Cartilage regeneration remains difficult due to a lack of blood vessels. Degradation of the
extracellular matrix (ECM) causes cartilage defects, and the ECM provides the natural …

Multileveled hierarchical hydrogel with continuous biophysical and biochemical gradients for enhanced repair of full‐thickness osteochondral defect

L Zhang, W Dai, C Gao, W Wei, R Huang… - Advanced …, 2023‏ - Wiley Online Library
The repair of hierarchical osteochondral defect requires sophisticated gradient
reestablishment; however, few strategies for continuous gradient casting consider the …

Rheology and texture analysis of gelatin/dialdehyde starch hydrogel carriers for curcumin controlled release

T Cui, Y Wu, C Ni, Y Sun, J Cheng - Carbohydrate Polymers, 2022‏ - Elsevier
A hydrogel carrier was prepared by synergistic cross-linking of dynamic imine bonds and
hydrogen bonds between gelatin and dialdehyde starch (DS). The dynamic gelation process …

A mechanical-assisted post-bioprinting strategy for challenging bone defects repair

J Yang, Z Chen, C Gao, J Liu, K Liu, X Wang… - Nature …, 2024‏ - nature.com
Bioprinting that can synchronously deposit cells and biomaterials has lent fresh impetus to
the field of tissue regeneration. However, the unavoidable occurrence of cell damage during …

Cellulose nanocrystal reinforced collagen-based nanocomposite hydrogel with self-healing and stress-relaxation properties for cell delivery

S Zhang, D Huang, H Lin, Y **ao, X Zhang - Biomacromolecules, 2020‏ - ACS Publications
While injectable in situ cross-linking collagen hydrogels offer great potential for applying
stem cell therapy to regenerate articular cartilage via minimally invasive procedures, the …

A metal–organic framework-incorporated hydrogel for delivery of immunomodulatory neobavaisoflavone to promote cartilage regeneration in osteoarthritis

Y Jiang, H Liao, L Yan, S Jiang, Y Zheng… - … Applied Materials & …, 2023‏ - ACS Publications
The treatment of osteoarthritis (OA)-related cartilage defects is a great clinical challenge due
to the complex pathogenesis of OA and poor self-repair ability of cartilage tissue. Combining …

Modeling and fabrication of silk fibroin–gelatin-based constructs using extrusion-based three-dimensional bioprinting

D Trucco, A Sharma, C Manferdini… - ACS biomaterials …, 2021‏ - ACS Publications
Robotic dispensing-based 3D bioprinting represents one of the most powerful technologies
to develop hydrogel-based 3D constructs with enormous potential in the field of regenerative …

A moldable thermosensitive hydroxypropyl chitin hydrogel for 3D cartilage regeneration in vitro and in vivo

Y Xu, Y Xu, B Bi, M Hou, L Yao, Q Du, A He, Y Liu… - Acta Biomaterialia, 2020‏ - Elsevier
Because of poor self-repair capacity, the repair of cartilage defect is always a great
challenge in clinical treatment. In vitro cartilage regeneration provides a potential strategy for …