Hydroxyurea and blood transfusion therapy for Sickle cell disease in South Asia: inconsistent treatment of a neglected disease

T Darshana, D Rees, A Premawardhena - Orphanet Journal of Rare …, 2021 - Springer
Background Hydroxyurea and blood transfusion therapies remain the main therapeutic
strategies for Sickle cell disease. Preliminary data suggest substantial variation and …

Frequency of β-thalassemia trait in families of thalassemia major patients, Lahore

T Majeed, MA Akhter, U Nayyar… - Journal of Ayub …, 2013 - demo.ayubmed.edu.pk
Background: Thalassemia major is one of the most common genetic disorders in Pakistan
and over five thousand new patients are added in the pool annually. This familial disease …

[PDF][PDF] The complete Spectrum of beta (β) thalassemia mutations in Bangladeshi population

GNN Sultana, R Begum, H Akhter, Z Shamim… - Austin Biomark …, 2016 - researchgate.net
Abstract Background: In Bangladesh, 3% people are carriers of β-thalassemia and 4%
people are E-β-thalassemia. However to date, very little data about HBB gene mutations in …

Distribution of β-thalassemia and other hemoglobinopathies in Bangladeshi university students and ready-made garment workers

MM Islam, F Hossain, N Sakib, Z Zeba… - … and Healthcare Policy, 2021 - Taylor & Francis
Background The inheritable thalassemia and other structural hemoglobinopathies are
prevalent globally. In Bangladesh, there is a scarcity of studies concerning thalassemia and …

Incidental screen positive findings in a prospective cohort study in Matlab, Bangladesh: Insights into expanded newborn screening for low-resource settings

MSQ Murphy, P Chakraborty, J Pervin… - Orphanet Journal of …, 2019 - Springer
Background Newborn screening programs are essential preventative public health
initiatives but are not widely available in low-resource settings. The objective of this study …

[PDF][PDF] Pattern of thalassemias and other hemoglobinopathies: a study in District Dera Ismail Khan, Pakistan

J Hussain, S Arif, S Zamir, MAJ Mahsud… - Gomal Journal of …, 2013 - gjms.com.pk
PATTERN OF THALASSEMIAS AND OTHER HEMOGLOBINOPATHIES: A STUDY IN
DISTRICT DERA ISMAIL KHAN, PAKISTAN Page 1 Gomal Journal of Medical Sciences July-December …

Assessment of serum calcium and phosphorus levels among transfusion-dependent beta thalassemia major patients on chelation therapy

S Shah - Journal of Postgraduate Medical Institute, 2015 - jpmi.org.pk
Objectives: to determine the levels of calcium and phosphorus in transfu-sion-dependant β-
thalassemia major patients who were on chelation therapy being followed at Fatimid …

[HTML][HTML] β-Thalassemia in Bangladesh: Current Status and Future Perspectives

A Mitro, D Hossain, MM Rahman, B Dam… - Thalassemia …, 2024 - mdpi.com
β-thalassemia, a life-threatening inheritable hemoglobin disorder caused by mutations in the
HBB gene, poses a significant public health challenge in the world. Although no …

Synergistic effect of simvastatin and romidepsin on gamma-globin gene induction

H Habibi, A Atashi, S Abroun… - Cell Journal …, 2018 - pmc.ncbi.nlm.nih.gov
Objective Hemoglobinopathies such as beta-thalassemia and sickle cell disease (SCD) are
inherited disorders that are caused by mutations in beta-globin chain. Gamma-globin gene …

Socio-demographic profile of patients admitted in Thalassemia care center of Chattogram Maa Shishu-O-General Hospital

T Barua, AK Das, R Sultana, D Das… - Chattagram Maa-O …, 2020 - banglajol.info
Background: Thalassemia is the most common hemoglobin disorder in the worldincluding
Bangladesh. Population migration and intermarriage between differentethnic groups have …