Towards translational optogenetics

A Bansal, S Shikha, Y Zhang - Nature Biomedical Engineering, 2023 - nature.com
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …

Flexible and stretchable light-emitting diodes and photodetectors for human-centric optoelectronics

S Chang, JH Koo, J Yoo, MS Kim, MK Choi… - Chemical …, 2024 - ACS Publications
Optoelectronic devices with unconventional form factors, such as flexible and stretchable
light-emitting or photoresponsive devices, are core elements for the next-generation human …

Light in diagnosis, therapy and surgery

SH Yun, SJJ Kwok - Nature biomedical engineering, 2017 - nature.com
Light and optical techniques have made profound impacts on modern medicine, with
numerous lasers and optical devices currently being used in clinical practice to assess …

Brain-machine interfaces: from basic science to neuroprostheses and neurorehabilitation

MA Lebedev, MAL Nicolelis - Physiological reviews, 2017 - journals.physiology.org
Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics

SI Park, DS Brenner, G Shin, CD Morgan… - Nature …, 2015 - nature.com
Optogenetics allows rapid, temporally specific control of neuronal activity by targeted
expression and activation of light-sensitive proteins. Implementation typically requires …

Blue-light receptors for optogenetics

A Losi, KH Gardner, A Möglich - Chemical reviews, 2018 - ACS Publications
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …

Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice

K Krawczyk, S Xue, P Buchmann, G Charpin-El-Hamri… - Science, 2020 - science.org
Sophisticated devices for remote-controlled medical interventions require an electrogenetic
interface that uses digital electronic input to directly program cellular behavior. We present a …

Applications of synthetic biology in medical and pharmaceutical fields

X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …

Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice

J Shao, S Xue, G Yu, Y Yu, X Yang, Y Bai… - Science translational …, 2017 - science.org
With the increasingly dominant role of smartphones in our lives, mobile health care systems
integrating advanced point-of-care technologies to manage chronic diseases are gaining …

Synthetic biology—the synthesis of biology

S Ausländer, D Ausländer… - Angewandte Chemie …, 2017 - Wiley Online Library
Synthetic biology concerns the engineering of man‐made living biomachines from
standardized components that can perform predefined functions in a (self‐) controlled …