Towards translational optogenetics
Optogenetics is widely used to interrogate the neural circuits underlying disease and has
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …
most recently been harnessed for therapeutic applications. The optogenetic toolkit consists …
Flexible and stretchable light-emitting diodes and photodetectors for human-centric optoelectronics
Optoelectronic devices with unconventional form factors, such as flexible and stretchable
light-emitting or photoresponsive devices, are core elements for the next-generation human …
light-emitting or photoresponsive devices, are core elements for the next-generation human …
Light in diagnosis, therapy and surgery
Light and optical techniques have made profound impacts on modern medicine, with
numerous lasers and optical devices currently being used in clinical practice to assess …
numerous lasers and optical devices currently being used in clinical practice to assess …
Brain-machine interfaces: from basic science to neuroprostheses and neurorehabilitation
MA Lebedev, MAL Nicolelis - Physiological reviews, 2017 - journals.physiology.org
Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …
neurophysiology, computer science, and engineering in an effort to establish real-time …
Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics
SI Park, DS Brenner, G Shin, CD Morgan… - Nature …, 2015 - nature.com
Optogenetics allows rapid, temporally specific control of neuronal activity by targeted
expression and activation of light-sensitive proteins. Implementation typically requires …
expression and activation of light-sensitive proteins. Implementation typically requires …
Blue-light receptors for optogenetics
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
Electrogenetic cellular insulin release for real-time glycemic control in type 1 diabetic mice
K Krawczyk, S Xue, P Buchmann, G Charpin-El-Hamri… - Science, 2020 - science.org
Sophisticated devices for remote-controlled medical interventions require an electrogenetic
interface that uses digital electronic input to directly program cellular behavior. We present a …
interface that uses digital electronic input to directly program cellular behavior. We present a …
Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Smartphone-controlled optogenetically engineered cells enable semiautomatic glucose homeostasis in diabetic mice
J Shao, S Xue, G Yu, Y Yu, X Yang, Y Bai… - Science translational …, 2017 - science.org
With the increasingly dominant role of smartphones in our lives, mobile health care systems
integrating advanced point-of-care technologies to manage chronic diseases are gaining …
integrating advanced point-of-care technologies to manage chronic diseases are gaining …
Synthetic biology—the synthesis of biology
S Ausländer, D Ausländer… - Angewandte Chemie …, 2017 - Wiley Online Library
Synthetic biology concerns the engineering of man‐made living biomachines from
standardized components that can perform predefined functions in a (self‐) controlled …
standardized components that can perform predefined functions in a (self‐) controlled …