Simple Summary Antibody-Drug Conjugates (ADCs) provide effective anti-cancer
treatments. ADC development requires the identification of appropriate tumour-associated …

Trastuzumab is a standard molecular targeted therapy for human epidermal growth factor
receptor 2 (HER2)-positive breast cancer, which can significantly improve the survival of …

MicroRNA‐221/222 (miRNA‐221/222, miR‐221/222) is a noncoding microRNA which is
widely distributed in eukaryotic organisms and deeply involved in the posttranscriptional …

MicroRNAs (miRNAs) are key epigenomic regulators of biological processes in animals and
plants. These small non coding RNAs form a complex networks that regulate cellular …

Malignant breast cancer (BC) remains incurable mainly due to the cancer cell metastasis,
which is mostly related to the status of Estrogen receptor alpha (ERα). However, our …

Simple Summary Breast cancer is the most diagnosed malignancy in woman worldwide
and, despite the availability of new innovative therapies, it remains the first cause of death …

In the brain, α‐synuclein (aSN) partitions between free unbound cytosolic and membrane
bound forms modulating both its physiological and pathological role and complicating its …

Netrin-4, a member of the Netrins family, is an important secreted protein that plays a role in
axonal outgrowth and migration orientation. It was initially described that Netrin-4 had a high …

MYB, a proto-oncogene, is overexpressed in prostate cancer (PCa) and promotes its growth,
aggressiveness, and resistance to androgen-deprivation therapy. Here, we examined the …

Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer, ranking as the
sixth most common cancer worldwide and the fourth leading cause of cancer-related deaths …