Cisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is
limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can …

Cisplatin is a clinically advanced and highly effective anticancer drug used in the treatment
of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer …

The clinical application of chemodynamic therapy is impeded by the insufficient intracellular
H2O2 level in tumor tissues. Herein, we developed a supramolecular nanoparticle via a …

Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

Administration of cisplatin, a common chemotherapeutic drug, has an inevitable side effect
of sensorineural hearing loss. The main etiologies are stria vascularis injury, spiral ganglion …

Computed tomography (CT), a diagnostic tool with clinical application, comprehensive
coverage, and low cost, is used in hospitals worldwide. However, CT imaging fails to …

Autophagy refers to the process involving the decomposition of intracellular components via
lysosomes. Autophagy plays an important role in maintaining and regulating cell …

Acute kidney injury (AKI) is characterized by mitochondrial dysfunction and activation of the
innate immune system. The cyclic GMP-AMP synthase (cGAS) stimulator of interferon genes …

Cisplatin is one of the most widely used chemotherapeutic agents for various solid tumors in
the clinic due to its high efficacy and broad spectrum. The antineoplastic activity of cisplatin …