The identification of actionable tumor antigens is indispensable for the development of
several cancer immunotherapies, including T cell receptor–transduced T cells and patient …

Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS
spectra from screening small molecules in fields such as environmental analysis, drug …

Most proteomic studies use liquid chromatography coupled to tandem mass spectrometry to
identify and quantify the peptides generated by the proteolysis of a biological sample …

The Comet database search software was initially released as an open source project in late
2012. Prior to that, Comet existed as the University of Washington's academic version of the …

Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Mass spectrometry-based proteomics has become the tool of choice for identifying and
quantifying the proteome of an organism. Though recent years have seen a tremendous …

Peptide identification via tandem mass spectrometry sequence database searching is a key
method in the array of tools available to the proteomics researcher. The ability to rapidly and …

This article covers the application of proteomic tools ('venomics','antivenomics' and 'venom
phenoty**') to study the composition and natural history of snake venoms, and the cross …

Peptide vaccines have shown great potential in cancer immunotherapy by targeting tumor
antigens and activating the patient's immune system to mount a specific response against …

Several milestones in biology have been achieved since the first publication of the
Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true …