Lung cancer is the most common malignancy and leads to around one-quarter of all cancer
deaths. Great advances have been achieved in the treatment of lung cancer with novel …

Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

1, 2, 4-Triazoles and their derivatives have a distinct place in the field of medicinal and
pharmaceutical chemistry. These are used as lead compounds for the synthesis of …

A novel series of triazine-triazole derivatives 7a–7m were synthesized, characterized by 1 H
NMR and evaluated for their α-glucosidase inhibitory activity. All the synthesized …

The triazole heterocycle is a privileged scaffold in medicinal chemistry, since its structure is
present in a large number of biologically active molecules, including several drugs currently …

Breast cancer is one of the most prevalent malignant diseases, and one of the main causes
of mortality among women across the world. Despite advances in chemotherapy, drug …

Abstract Fused heterocyclic systems with 1, 2, 4‐triazole scaffold arouse great interest from
researchers in the branch of heterocyclic and medical chemistry because of their wide …

This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone,
examples of bioactive natural products that still being under biological evaluation and …

Frequent oncogenic mutations have been identified in MAPK (mitogen-activated protein
kinase) signaling pathway components. As a result, MAPK pathway is associated with …

Two series of novel 1, 2, 3-triazole based artemisinin derivatives were designed,
synthesized via a copper (I)-catalyzed azide alkyne cycloaddition (CuAAC) reaction and …