Evolution of biochip technology: A review from lab-on-a-chip to organ-on-a-chip
Following the advancements in microfluidics and lab-on-a-chip (LOC) technologies, a novel
biomedical application for microfluidic based devices has emerged in recent years and …
biomedical application for microfluidic based devices has emerged in recent years and …
Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …
[HTML][HTML] Cardiovascular disease models: a game changing paradigm in drug discovery and screening
Cardiovascular disease is the leading cause of death worldwide. Although investment in
drug discovery and development has been sky-rocketing, the number of approved drugs has …
drug discovery and development has been sky-rocketing, the number of approved drugs has …
Design and fabrication of drug‐delivery systems toward adjustable release profiles for personalized treatment
Advanced polymeric controlled delivery systems are designed to effectively treat chronic
diseases by adjusting the temporal profile of drug release. Most conventional controlled …
diseases by adjusting the temporal profile of drug release. Most conventional controlled …
Drug toxicity evaluation based on organ-on-a-chip technology: a review
Y Cong, X Han, Y Wang, Z Chen, Y Lu, T Liu, Z Wu… - Micromachines, 2020 - mdpi.com
Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …
A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it
A Varone, JK Nguyen, L Leng, R Barrile, J Sliz… - Biomaterials, 2021 - Elsevier
Successful translation of in vivo experimental data to human patients is an unmet need and
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …
Advancing Intelligent Organ‐on‐a‐Chip Systems with Comprehensive In Situ Bioanalysis
X Li, H Zhu, B Gu, C Yao, Y Gu, W Xu… - Advanced …, 2024 - Wiley Online Library
In vitro models are essential to a broad range of biomedical research, such as pathological
studies, drug development, and personalized medicine. As a potentially transformative …
studies, drug development, and personalized medicine. As a potentially transformative …
Recent advances in microfluidics for drug screening
J Sun, AR Warden, X Ding - Biomicrofluidics, 2019 - pubs.aip.org
With ever increasing drug resistance and emergence of new diseases, demand for new drug
development is at an unprecedented urgency. This fact has led to extensive recent efforts to …
development is at an unprecedented urgency. This fact has led to extensive recent efforts to …
Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism
Oxygen (O2) quantification is essential for assessing cell metabolism, and its consumption in
cell culture is an important indicator of cell viability. Recent advances in microfluidics have …
cell culture is an important indicator of cell viability. Recent advances in microfluidics have …
Gut-on-chip for ecological and causal human gut microbiome research
There is a growing interest to understand if and how the gut microbiome is causally linked to
the pathogenesis and/or progression of diseases. While in vitro cell line models are …
the pathogenesis and/or progression of diseases. While in vitro cell line models are …