[HTML][HTML] Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging

ES Gonos, M Kapetanou, J Sereikaite, G Bartosz… - Aging (Albany …, 2018‏ - ncbi.nlm.nih.gov
Non-enzymatic protein modifications occur inevitably in all living systems. Products of such
modifications accumulate during aging of cells and organisms and may contribute to their …

A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans

R Jung, MC Lechler, A Fernandez-Villegas… - PLoS …, 2023‏ - journals.plos.org
During aging, proteostasis capacity declines and distinct proteins become unstable and can
accumulate as protein aggregates inside and outside of cells. Both in disease and during …

Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice

Y Yagisawa, K Suita, Y Ohnuki, M Ishikawa… - PLoS …, 2020‏ - journals.plos.org
Occlusal disharmony leads to morphological changes in the hippocampus and osteopenia
of the lumbar vertebra and long bones in mice, and causes stress. Various types of stress …

Characterization of plasma SDS-protein aggregation profile of patients with Heart Failure with preserved ejection fraction

M Gouveia, C Schmidt, M Teixeira, M Lopes… - Journal of …, 2023‏ - Springer
This study characterizes the plasma levels and composition of SDS-resistant aggregates
(SRAs) in patients with heart failure with preserved ejection fraction (HFpEF) to infer …

Comparing the effect of Centella asiatica L. and Acalypha indica L. treatment to carbonyl and glutathione level in the brains of old rats

N Mudjihartini, R Paramita, AMK Siregar… - Acta Biochimica …, 2022‏ - jurnal.pbbmi.org
Background: Free radicals in excessive concentrations damages cells and accelerate the
aging process. Antioxidants found in Centella asiatica (CA) and Acalypha indica (AI) have …