Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

The human macula uniquely concentrates three carotenoids: lutein, zeaxanthin, and meso-
zeaxanthin. Lutein and zeaxanthin must be obtained from dietary sources such as green …

Steroid hormones regulate diverse physiological functions such as reproduction, blood salt
balance, maintenance of secondary sexual characteristics, response to stress, neuronal …

Among the more than 750 carotenoids identified in nature, only lutein, zeaxanthin, meso-
zeaxanthin, and their oxidative metabolites are selectively accumulated in the macula lutea …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

There is unequivocal evidence of an inverse association between plasma high-density
lipoprotein (HDL) cholesterol concentrations and the risk of cardiovascular disease, a …

Aims Retention of low-density lipoprotein (LDL) cholesterol beneath the arterial endothelium
initiates an inflammatory response culminating in atherosclerosis. Since the overlying …

Malignant tumors display remarkable heterogeneity to the extent that even at the same
tissue site different types of cells with varying genetic background may be found. In contrast …

Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder
associated with mechanical stress and aging but also a 'metabolic syndrome'in which …