Skin wounds greatly affect the global healthcare system, creating a substantial burden on
the economy and society. Moreover, the situation is exacerbated by low healing rates, which …

As the body's integumentary system, the skin is vulnerable to injuries. The subsequent
wound healing processes aim to restore dermal and epidermal integrity and functionality. To …

Psoriasis is a chronic inflammatory disease with a strong genetic component that can be
triggered by environmental factors. Disease pathogenesis is mainly driven by type 1 and …

Skin is our primary interface with the environment, and T cells are crucial for orchestrating
host immune responses against pathogenic microorganisms at this site. Effective skin …

The chemokine superfamily consists of a large number of ligands and receptors. At first
glance, this family appears redundant and their ligand-receptor relationships promiscuous …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Purpose To determine whether density and distribution of tumor-infiltrating lymphocytes
(TILs; TIL grade) is an independent predictor of sentinel lymph node (SLN) status and …

Chemokines and chemokine receptors orchestrate cell migration and homing in the body.
Humans have at least 44 chemokines that are further classified into four subfamilies based …

Inflammation is usually analysed from the perspective of tissue-infiltrating leukocytes.
Microvascular endothelial cells at a site of inflammation are both active participants in and …

Abstract Forkhead box P3 (FOXP3)+ regulatory T (TReg) cells prevent autoimmune disease,
maintain immune homeostasis and modulate immune responses during infection. To …