Chronic early life stress induced by limited bedding and nesting (LBN) material in rodents: critical considerations of methodology, outcomes and translational potential

CD Walker, KG Bath, M Joels, A Korosi, M Larauche… - Stress, 2017 - Taylor & Francis
The immediate and long-term effects of exposure to early life stress (ELS) have been
documented in humans and animal models. Even relatively brief periods of stress during the …

The neurodevelopmental basis of early childhood disruptive behavior: Irritable and callous phenotypes as exemplars

LS Wakschlag, SB Perlman, RJ Blair… - American journal of …, 2018 - Am Psychiatric Assoc
The arrival of the Journal's 175th anniversary occurs at a time of recent advances in
research, providing an ideal opportunity to present a neurodevelopmental roadmap for …

Family environment, neurodevelopmental risk, and the environmental influences on child health outcomes (ECHO) initiative: looking back and moving forward

NR Bush, LS Wakschlag, KZ LeWinn… - Frontiers in …, 2020 - frontiersin.org
The family environment, with all its complexity and diverse components, plays a critical role
in sha** neurodevelopmental outcomes in children. Herein we review several domains of …

The influence of early adversity on self-regulation and student-teacher relationships in preschool

AM Loomis - Early Childhood Research Quarterly, 2021 - Elsevier
Nearly half of young children nationally have some sort of preschool experience by the time
they enter kindergarten. Many of these children have experienced one or more types of …

Early secure attachment as a protective factor against later cognitive decline and dementia

E Walsh, Y Blake, A Donati, R Stoop… - Frontiers in Aging …, 2019 - frontiersin.org
The etiology of neurodegenerative disorders such as dementia is complex and incompletely
understood. Interest in a developmental perspective to these pathologies is gaining …

Linking irritability and functional brain networks: A transdiagnostic case for expanding consideration of development and environment in RDoC

AN Nielsen, LS Wakschlag, ES Norton - Neuroscience & Biobehavioral …, 2021 - Elsevier
Abstract The National Institute of Mental Health Research Domain Criteria (RDoC)
framework promotes the dimensional and transdiagnostic operationalization of …

Differences on brain connectivity in adulthood are present in subjects with iron deficiency anemia in infancy

C Algarin, KD Karunakaran, S Reyes… - Frontiers in aging …, 2017 - frontiersin.org
Iron deficiency continues to be the most prevalent micronutrient deficit worldwide. Since iron
is involved in several processes including myelination, dopamine neurotransmission and …

The effects of early life adversity on growth, maturation, and steroid hormones in male and female rats

SR Eck, CS Ardekani, M Salvatore… - European Journal of …, 2020 - Wiley Online Library
Early life adversity is a risk factor for psychiatric disorders, yet the mechanisms by which
adversity increases this risk are still being delineated. Here, we used a limited bedding and …

[HTML][HTML] Examining the relationship between fetal cortical thickness, gestational age, and maternal psychological distress

J De Asis-Cruz, JH Kim, D Krishnamurthy… - Developmental …, 2023 - Elsevier
In utero exposure to maternal stress, anxiety, and depression has been associated with
reduced cortical thickness (CT), and CT changes, in turn, to adverse neuropsychiatric …

[HTML][HTML] Resting state brain dynamics: Associations with childhood sexual abuse and major depressive disorder

EL Belleau, TAW Bolton, RH Kaiser, R Clegg… - NeuroImage: Clinical, 2022 - Elsevier
Early life stress (ELS) and major depressive disorder (MDD) share neural network
abnormalities. However, it is unclear how ELS and MDD may separately and/or jointly relate …