Current applications of nanoparticles in infectious diseases
For decades infections have been treated easily with drugs. However, in the 21st century,
they may become lethal again owing to the development of antimicrobial resistance …
they may become lethal again owing to the development of antimicrobial resistance …
Nano-therapeutics: A revolution in infection control in post antibiotic era
With the arrival of antibiotics 70 years ago, meant a paradigm shift in overcoming infectious
diseases. For decades, drugs have been used to treat different infections. However, with …
diseases. For decades, drugs have been used to treat different infections. However, with …
Navigating bioactivity space in anti-tubercular drug discovery through the deployment of advanced machine learning models and cheminformatics tools: a molecular …
Mycobacterium tuberculosis is the bacterial strain that causes tuberculosis (TB). However,
multidrug-resistant and extensively drug-resistant tuberculosis are significant obstacles to …
multidrug-resistant and extensively drug-resistant tuberculosis are significant obstacles to …
Structure-based virtual screening, molecular dynamics simulation and MM-PBSA toward identifying the inhibitors for two-component regulatory system protein NarL of …
N Kumar, R Srivastava, A Prakash… - Journal of Biomolecular …, 2020 - Taylor & Francis
The nitrate/nitrite response regulatory protein NarL belongs to the two-component regulatory
system of Mycobacterium tuberculosis (MTB), plays a crucial role in anaerobic survival of …
system of Mycobacterium tuberculosis (MTB), plays a crucial role in anaerobic survival of …
Carbon nanotropes: a contemporary paradigm in drug delivery
Discovery of fullerenes and other nanosized carbon allotropes has opened a vast new field
of possibilities in nanotechnology and has become one of the most promising research …
of possibilities in nanotechnology and has become one of the most promising research …
Synthesis of exfoliated multilayer graphene and its putative interactions with SARS-CoV-2 virus investigated through computational studies
Our work investigates the interaction of synthesized graphene with the SARS-CoV-2 virus
using molecular docking and molecular dynamics (MD) simulation method. The layer …
using molecular docking and molecular dynamics (MD) simulation method. The layer …
Enhancing cancer drug development with xanthone derivatives: A QSAR approach and comparative molecular docking investigations
Xanthone compounds are known to have diverse pharmacological activities, including anti-
inflammatory, anticancer properties. However, they face challenges such as poor water …
inflammatory, anticancer properties. However, they face challenges such as poor water …
Revelation of enzyme activity of mutant pyrazinamidases from Mycobacterium tuberculosis upon binding with various metals using quantum mechanical approach
N Rasool, W Husssain, YD Khan - Computational biology and chemistry, 2019 - Elsevier
Pyrazinamide (PZA) is one of the most potent bacteriostatic drug against tuberculosis, a
deadliest disease with high mortality and morbidity rate. PZA metabolizes into its active form …
deadliest disease with high mortality and morbidity rate. PZA metabolizes into its active form …
Carbon nanomaterials: a new way against tuberculosis
Introduction: Tuberculosis (TB) remains one of the most alarming worldwide infectious
diseases primarily in low-income countries, where the infection shows a higher and …
diseases primarily in low-income countries, where the infection shows a higher and …
Density functional study on noncovalent functionalization of pyrazinamide chemotherapeutic with graphene and its prototypes
N Saikia, RC Deka - New Journal of Chemistry, 2014 - pubs.rsc.org
We perform density functional studies to comprehend the structure and energetics of the
interaction of the drug pyrazinamide (PZA) with graphene-based nanomaterials using a …
interaction of the drug pyrazinamide (PZA) with graphene-based nanomaterials using a …