Biofilm formation in periprosthetic joint infections

A Staats, D Li, AC Sullivan, P Stoodley - Annals of joint, 2021 - pmc.ncbi.nlm.nih.gov
Formation of microbial biofilms has long been implicated in the occurrence of periprosthetic
joint infections (PJIs). Despite the widespread acknowledgment of the severity of these …

Different concentrations of vancomycin with gentamicin loaded PMMA to inhibit biofilm formation of Staphylococcus aureus and their implications

MA Pedroni, VST Ribeiro, J Cieslinski… - Journal of Orthopaedic …, 2024 - Elsevier
Background This study aimed to evaluate different concentrations of vancomycin and/or
gentamicin loaded polymethylmethacrylate (PMMA) against biofilm formation of …

Ultrastructure imaging of Pseudomonas aeruginosa lawn biofilms and eradication of the tobramycin-resistant variants under in vitro electroceutical treatment

V Lochab, TH Jones, DH Dusane, CW Peters… - Scientific reports, 2020 - nature.com
Electrochemically generated bactericidal compounds have been shown to eradicate
bacterial lawn biofilms through electroceutical treatment. However, the ultrastructure of …

[HTML][HTML] Potential of Bacterial Cellulose Chemisorbed with Anti-Metabolites, 3-Bromopyruvate or Sertraline, to Fight against Helicobacter pylori Lawn Biofilm

P Krzyżek, G Gościniak, K Fijałkowski, P Migdał… - International Journal of …, 2020 - mdpi.com
Helicobacter pylori is a bacterium known mainly of its ability to cause persistent
inflammations of the human stomach, resulting in peptic ulcer diseases and gastric cancers …

Calcium sulfate beads made with antibacterial essential oil-water emulsions exhibit growth inhibition against Staphylococcus aureus in agar pour plates

AN Hawkins, SJ Licea, SA Sleeper, MC Swearingen - Plos one, 2022 - journals.plos.org
Calcium sulfate bone void filler beads are fully absorbable in the body, and are often used in
complicated orthopedic infection cases to release a relatively high dose of antibiotics locally …

Novel aminoglycoside-tolerant phoenix colony variants of Pseudomonas aeruginosa

D Sindeldecker, K Moore, A Li… - Antimicrobial agents …, 2020 - journals.asm.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen and is known to produce
biofilms. We previously showed the emergence of colony variants in the presence of …

[HTML][HTML] In vivo efficacy of a refillable intrawound drug delivery device in a sheep model of biofilm-compromised open fracture-related infection

D Williams, D Rothberg, W Kay, L Nehring, R Falconer… - Biofilm, 2025 - Elsevier
Open fracture-related infection challenges persist in healthcare. From the time open
fractures were defined∼ 40 years ago, infection rates have gone essentially unchanged …

In vitro efficacy of antibiotic loaded calcium sulfate beads (Stimulan Rapid Cure) against polymicrobial communities and individual bacterial strains derived from …

J Fletcher, R Porter, Z Boulton… - Journal of Medical …, 2022 - microbiologyresearch.org
Introduction. Diabetic foot infection (DFI) is the main reason for diabetes-related
hospitalisation and is a major cause of diabetes-related amputation. DFIs are often …

[HTML][HTML] The use of antibiotic-loaded calcium sulphate beads in debridement, antibiotics, and implant retention (DAIR) for periprosthetic infections: a retrospective …

IK Sigmund, AJR Palmer, AJ Hotchen… - Acta …, 2024 - pmc.ncbi.nlm.nih.gov
Background and purpose We aimed to compare the effect of calcium sulphate (CS) beads
loaded with antibiotics on infection eradication in debridement, antibiotics, and implant …

[HTML][HTML] Prevention and Killing Efficacy of Carbapenem Resistant Enterobacteriaceae (CRE) and Vancomycin Resistant Enterococci (VRE) Biofilms by Antibiotic …

P Stoodley, J Brooks, CW Peters, N Jiang, CP Delury… - Materials, 2020 - mdpi.com
Carbapenem-resistant Enterobacteriaceae (CRE) and vancomycin-resistant Enterococci
(VRE) have emerged as multidrug-resistant (MDR) pathogens associated with periprosthetic …