Host–transposon interactions: conflict, cooperation, and cooption

RL Cosby, NC Chang, C Feschotte - Genes & development, 2019 - genesdev.cshlp.org
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …

Transposable element domestication as an adaptation to evolutionary conflicts

D Jangam, C Feschotte, E Betrán - Trends in Genetics, 2017 - cell.com
Transposable elements (TEs) are selfish genetic units that typically encode proteins that
enable their proliferation in the genome and spread across individual hosts. Here we review …

Genomic insights into the phylogeny and biomass-degrading enzymes of rumen ciliates

Z Li, X Wang, Y Zhang, Z Yu, T Zhang, X Dai… - The ISME …, 2022 - academic.oup.com
Understanding the biodiversity and genetics of gut microbiomes has important implications
for host physiology and industrial enzymes, whereas most studies have been focused on …

Programmed chromosome fragmentation in ciliated protozoa: multiple means to chromosome ends

M Bétermier, LA Klobutcher, E Orias - Microbiology and Molecular …, 2023 - Am Soc Microbiol
Ciliated protozoa undergo large-scale developmental rearrangement of their somatic
genomes when forming a new transcriptionally active macronucleus during conjugation …

A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing

C Wang, T Solberg, XX Maurer-Alcala, EC Swart… - Cell reports, 2022 - cell.com
In animal germlines, transposons are silenced at the transcriptional or post-transcriptional
level to prevent deleterious expression. Ciliates employ a more direct approach by …

The completed macronuclear genome of a model ciliate Tetrahymena thermophila and its application in genome scrambling and copy number analyses

Y Sheng, L Duan, T Cheng, Y Qiao, NA Stover… - Science China Life …, 2020 - Springer
The ciliate Tetrahymena thermophila has been a powerful model system for molecular and
cellular biology. However, some investigations have been limited due to the incomplete …

The macronuclear genome of Stentor coeruleus reveals tiny introns in a giant cell

MM Slabodnick, JG Ruby, SB Reiff, EC Swart, S Gosai… - Current Biology, 2017 - cell.com
The giant, single-celled organism Stentor coeruleus has a long history as a model system for
studying pattern formation and regeneration in single cells. Stentor [1, 2] is a heterotrichous …

Programmed genome rearrangements in ciliates

I Rzeszutek, XX Maurer-Alcalá, M Nowacki - Cellular and Molecular Life …, 2020 - Springer
Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …

A practical reference for studying meiosis in the model ciliate Tetrahymena thermophila

M Tian, X Cai, Y Liu, M Liucong… - Marine Life Science & …, 2022 - Springer
Meiosis is a critical cell division program that produces haploid gametes for sexual
reproduction. Abnormalities in meiosis are often causes of infertility and birth defects (eg …

[HTML][HTML] Comprehensive chromosome end remodeling during programmed DNA elimination

J Wang, GMB Veronezi, Y Kang, M Zagoskin… - Current Biology, 2020 - cell.com
Germline and somatic genomes are in general the same in a multicellular organism.
However, programmed DNA elimination leads to a reduced somatic genome compared to …