Revisiting the expression of BDNF and its receptors in mammalian development
Brain-derived neurotrophic factor (BDNF) promotes the survival and functioning of neurons
in the central nervous system and contributes to proper functioning of many non-neural …
in the central nervous system and contributes to proper functioning of many non-neural …
BDNF Modulation by microRNAs: An Update on the Experimental Evidence
MicroRNAs can interfere with protein function by suppressing their messenger RNA
translation or the synthesis of its related factors. The function of brain-derived neurotrophic …
translation or the synthesis of its related factors. The function of brain-derived neurotrophic …
Role of Post-Transcriptional Regulation in Learning and Memory in Mammals
CM Di Liegro, G Schiera, G Schirò, I Di Liegro - Genes, 2024 - mdpi.com
After many decades, during which most molecular studies on the regulation of gene
expression focused on transcriptional events, it was realized that post-transcriptional control …
expression focused on transcriptional events, it was realized that post-transcriptional control …
C-terminal peptide of preproorexin enhances brain-derived neurotrophic factor expression in rat cerebrocortical cells and recognition memory in mice
H Tsuneki, K Honda, Y Sekine, K Yahata… - European Journal of …, 2024 - Elsevier
During the production of orexin A and B from preproorexin, a common precursor protein, in
hypothalamic orexin neurons, C-terminal peptide (herein called preproorexin C-peptide) is …
hypothalamic orexin neurons, C-terminal peptide (herein called preproorexin C-peptide) is …
Neuron-selective and activity-dependent splicing of BDNF exon I–IX pre-mRNA
M Fukuchi, Y Shibasaki, Y Akazawa… - Neurochemistry …, 2024 - Elsevier
Brain-derived neurotrophic factor (BDNF) is essential for numerous neuronal functions,
including learning and memory. The expression of BDNF is regulated by distinctive …
including learning and memory. The expression of BDNF is regulated by distinctive …
Selective Noradrenergic Activation of BDNF Translation by Mirtazapine
Antidepressants are known for their neurotrophic effects, particularly through the regulation
of brain-derived neurotrophic factor (BDNF) expression. Mirtazapine, a tetracyclic …
of brain-derived neurotrophic factor (BDNF) expression. Mirtazapine, a tetracyclic …
Chemical LTP induces confinement of BDNF mRNA under dendritic spines and BDNF protein accumulation inside the spines
G Bimbi, E Tongiorgi - Frontiers in Molecular Neuroscience, 2024 - frontiersin.org
The neurotrophin brain-derived neurotrophic factor (BDNF) plays a key role in neuronal
development and synaptic plasticity. The discovery that BDNF mRNA can be transported in …
development and synaptic plasticity. The discovery that BDNF mRNA can be transported in …
Expression Profiles of Brain-Derived Neurotrophic Factor Splice Variants in the Hippocampus of Alzheimer's Disease Model Mouse
Y Matsuoka, H Nakasone, R Kasahara… - Biological and …, 2024 - jstage.jst.go.jp
Dysregulation of brain-derived neurotrophic factor (BDNF) has been implicated in
Alzheimer's disease (AD). In this study, we investigated the temporal dynamics of BDNF …
Alzheimer's disease (AD). In this study, we investigated the temporal dynamics of BDNF …
Characterisation of novel transcripts in the 3'region of L-type calcium channel genes in human brain
H Lee - 2023 - ora.ox.ac.uk
The alpha-1 subunit (CACNA1 family) of L-type voltage-gated calcium channels (LTCCs)
play significant roles in brain function and neuropsychiatric disorders. Transcription of …
play significant roles in brain function and neuropsychiatric disorders. Transcription of …
[BUCH][B] Studies on the modulation of gene expression via 3 UTR editing to model and treat neurological disease
S Olfat - 2024 - search.proquest.com
It is increasingly clear that gene expression levels play a critical role in human health.
Forexample, genome-wide association studies (GWAS) reveal that at least 93% of …
Forexample, genome-wide association studies (GWAS) reveal that at least 93% of …