The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome 2
(SARS-CoV-2), has been one of the most devastating pandemics of recent times. The lack of …

Abstract Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the pathogen
that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or …

Newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a
global pandemic with astonishing mortality and morbidity. The high replication and …

SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over
170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and …

Since its outbreak in late 2019, the COVID-19 pandemic has drawn enormous attention
worldwide as a consequence of being the most disastrous infectious disease in the past …

The most advanced antiviral molecules addressing major SARS-CoV-2 targets (Main
protease, Spike protein, and RNA polymerase), compared with proteins of other human …

The main protease (Mpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the cause of coronavirus disease (COVID-19), is an ideal target for pharmaceutical …

Suppression of type I interferon (IFN) response is one pathological outcome of the infection
of highly pathogenic human coronaviruses. To effect this, severe acute respiratory syndrome …

The SARS-CoV-2 main protease (Mpro) plays an essential role in the coronavirus lifecycle
by catalyzing hydrolysis of the viral polyproteins at specific sites. Mpro is the target of drugs …