Oxygen is vital for cellular metabolism; therefore, the hypoxic conditions encountered at high
altitude affect all physiological functions. Acute hypoxia activates the adrenergic system and …

Obesity is a worldwide pandemic contributing to the hypertensive state and to the
cardiovascular morbidity leading to an increase in hospitalizations, events and cost to the …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Background Sodium-glucose cotransporter-2 inhibitors reduce blood pressure (BP) and
renal and cardiovascular events in patients with type 2 diabetes through not fully elucidated …

Climie et al Macrovasculature and Microvasculature in HTN and T2D 1139 million global
disability-adjusted life years, an increase of 11.7% from 2005. 9 Because hypertension …

Cardiovascular disease (CVD) remains the most prevalent cause of premature death
worldwide. It had been suspected for decades that increased activity of the sympathetic …

Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are incurable
autoimmune diseases characterized by chronic inflammation of the gastrointestinal tract …

Endothelial dysfunction and autonomic nervous system dysfunction are both risk factors for
atherosclerosis. There is evidence demonstrating that there is a close interrelationship …

The peripheral nervous system takes an active part in inflammatory processes by regulating
effector cell function and reallocation of energy to the immune system. During acute …

Experimental and clinical studies have clearly shown the role of the sympathetic nervous
system in the pathophysiology of several cardiovascular and non-cardiovascular diseases …