[HTML][HTML] HIV-1 drug resistance mutations: an updated framework for the second decade of HAART

RW Shafer, JM Schapiro - AIDS reviews, 2008 - ncbi.nlm.nih.gov
More than 200 mutations are associated with antiretroviral resistance to drugs belonging to
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …

[PDF][PDF] Characterization and structural analysis of HIV-1 integrase conservation

F Ceccherini-Silberstein, I Malet, R D'Arrigo, A Antinori… - Aids Rev, 2009 - researchgate.net
The HIV-1 integrase, responsible for the chromosomal integration of the newly synthesized
doublestranded viral DNA into the host genomic DNA, represents a new and important …

Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors

L Tambuyzer, H Azijn, LT Rimsky, J Vingerhoets… - 2009 - journals.sagepub.com
Background Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are an important
component of antiretroviral therapy for HIV type-1 (HIV-1)-infected patients. Development of …

What do molecules do when we are not looking? State sequence analysis for stochastic chemical systems

P Levin, J Lefebvre, TJ Perkins - Journal of The Royal …, 2012 - royalsocietypublishing.org
Many biomolecular systems depend on orderly sequences of chemical transformations or
reactions. Yet, the dynamics of single molecules or small-copy-number molecular systems …

[LIVRE][B] Computing most probable sequences of state transitions in continuous-time Markov systems

P Levin - 2012 - search.proquest.com
Continuous-time Markov chains (CTMC's) form a convenient mathematical framework for
analyzing random systems across many different disciplines. A specific research problem …