Endovascular thrombectomy (EVT) is well established as a highly effective treatment for
acute ischemic stroke (AIS) due to proximal, large vessel occlusions (PLVOs). With iterative …

White matter vasculature plays a major role in the pathophysiology of permanent
neurological deficits following a stroke or progressive cognitive alteration related to small …

Background Preclinical data suggest circadian variation in ischemic stroke progression, with
more active cell death and infarct growth in rodent models with inactive phase (daytime) …

Enlarged perivascular spaces (PVS) are considered a biomarker for vascular pathology and
are observed in normal aging and neurological conditions; however, research on the role of …

The locus and extent of brain damage in the event of vascular insult can be quantitatively
established quickly and easily with vascular atlases. Although highly anticipated by …

Background and Objectives Female patients tend to have greater disability and worse long-
term outcomes after stroke than male patients. To date, the biological basis of sex difference …

Objective To define the role and risks associated with white matter hyperintensity (WMH)
load in a stroke population with respect to recurrent stroke and mortality after ischemic …

Strokes are one of the global leading causes of physical or mental impairment and fatality,
classified into hemorrhagic and ischemic strokes. Ischemic strokes happen when a …

Perivascular spaces (PVSs) are fluid-filled spaces surrounding penetrating blood vessels in
the brain and are an integral pathway of the glymphatic system. A PVS and the enclosed …

A previous study we reported in this journal suggested that left and right-handers may differ
in their patterns of lateralization for different language tasks (Woodhead et al. 2019 R. Soc …