Age is a major risk factor for cancer, but how aging impacts tumor control remains unclear. In
this study, we establish that aging of the immune system, regardless of the age of the stroma …

Visual impairment and blindness are a growing public health problem as they reduce the life
quality of millions of people. The management and treatment of these diseases represent …

Pattern recognition receptors (PRRs) recognize danger signals such as PAMPs/MAMPs and
DAMPs to initiate a protective immune response. TLRs, NLRs, CLRs, and RLRs are well …

Background Declined skeletal muscle mass and function are inevitable consequences of
long‐term diabetes and bring about many adverse events. Muscle fibre atrophy and …

The number of senescent vascular endothelial cells increases during aging and their
dysfunctional phenotype contributes to age‐related cardiovascular disease. Identification of …

Despite remarkable breakthroughs in pharmacotherapy, many potential therapies for aging
remain unexplored. Punicalin (PUN), an ellagitannin component, exerts anti‐inflammatory …

Diabetic nephropathy (DN) is a complication of diabetes and is mainly characterized by
renal fibrosis, which could be attributed to chronic kidney inflammation. Stimulator of …

Rejuvenation of diabetic macular edema with senolytic therapy | Nature Medicine Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

Endothelial senescence, aging-related inflammation, and mitochondrial dysfunction are
prominent features of vascular aging and contribute to the development of aging-associated …

Vascular calcification is a prevalent hallmark of cardiovascular risk in elderly and diabetic
individuals. Senescent vascular smooth muscle cells (VSMCs) participate in calcification; …