This review provides an overview of the clinical issue of poorly controlled postoperative pain
and therapeutic approaches that may help to address this common unresolved health-care …

Acute postoperative pain is followed by persistent pain in 10–50% of individuals after
common operations, such as groin hernia repair, breast and thoracic surgery, leg …

Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

The development of chronic pain is considered a major complication after surgery. Basic
science research in animal models helps us understand the transition from acute to chronic …

Although postoperative pain remains incompletely controlled in some settings, increased
understanding of its mechanisms and the development of several therapeutic approaches …

Background The present article has been written to convey concepts of anaesthetic care
within the context of an Enhanced Recovery After Surgery (ERAS) programme, thus aligning …

The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …

Background: Chronic postsurgical pain can severely impair patient health and quality of life.
This systematic review update evaluated the effectiveness of systemic drugs to prevent …

The transition from acute to chronic pain appears to occur in discrete pathophysiological and
histopathological steps. Stimuli initiating a nociceptive response vary, but receptors and …

BACKGROUND The PROSPECT (PROcedure SPEcific Postoperative Pain ManagemenT)
Working Group is a global collaboration of surgeons and anaesthesiologists formulating …