The transition from normal to chronic pain is believed to involve alterations in several brain
areas that participate in the perception of pain. These plastic changes are then responsible …

Abstract The recently proposed Analgesic, Anesthetic, and Addiction Clinical Trial
Translations, Innovations, Opportunities, and Networks (ACTTION)-American Pain Society …

Background Gabapentin is commonly used to treat neuropathic pain (pain due to nerve
damage). This review updates a review published in 2014, and previous reviews published …

Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …

Low back pain (LBP) is one of the major disabling health conditions among older adults
aged 60 years or older. While most causes of LBP among older adults are non-specific and …

Chronic pain is a common public health problem that has a detrimental impact on patient
health, quality of life (QoL), and function, and poses a substantial socioeconomic burden …

The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …

Background Persistent pain is measured by means of self-report, the sole reliance on which
hampers diagnosis and treatment. Functional magnetic resonance imaging (fMRI) holds …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

Chronic pain is associated with neuronal plasticity. Here we use resting-state functional
magnetic resonance imaging to investigate functional changes in patients suffering from …