Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Macroautophagy/autophagy is an evolutionarily conserved cellular degradation process that
targets cytoplasmic materials including cytosol, macromolecules and unwanted organelles …

Autophagy maintains cellular homeostasis during low energy states. According to the
current understanding, glucose-depleted cells induce autophagy through AMPK, the primary …

Autophagosome biogenesis involves de novo formation of a membrane that elongates to
sequester cytoplasmic cargo and closes to form a double-membrane vesicle (an …

Autophagy is a primarily degradative pathway that takes place in all eukaryotic cells. It is
used for recycling cytoplasm to generate macromolecular building blocks and energy under …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

One mechanism by which communication between the endoplasmic reticulum (ER) and
mitochondria is achieved is by close juxtaposition between these organelles via …

During the process of autophagy, cytoplasmic materials are sequestered by double-
membrane structures, the autophagosomes, and then transported to a lytic compartment to …

Autophagy is a process of self-degradation of cellular components in which double-
membrane autophagosomes sequester organelles or portions of cytosol and fuse with …

The autophagy-related (Atg) proteins play a key role in the formation of autophagosomes,
the hallmark of autophagy. The function of the cluster composed by Atg2, Atg18, and …