Autophagy is an abnormal protein degradation and recycling process that is impaired in
various neurological diseases like Alzheimer's disease (AD), Parkinson's disease (PD), and …

Background Accumulation of amyloid beta, tau hyperphosphorylation, and microglia
activation are the three highly acknowledged pathological factors of Alzheimer's disease …

Simple Summary This review mainly focuses on epigenetic changes in a few selective
genes associated with insulin insensitivity in the periphery and how this peripheral insulin …

A significant quantity of substance P (SP) and its receptor neurokinin (NK) receptors are
found in the brain. SP is a neuropeptide distributed in the central nervous system and …

Epilepsy is a common neurological disorder characterized by recurrent seizures with
excessive and abnormal neuronal discharges. Epileptogenesis is usually involved in …

Follicle-stimulating hormone (FSH) acts by binding to FSHRs expressed on ovarian
granulosa cells and produces estradiol. FSH is essential for female fertility because mice …

Huntington's disease (HD) is a progressive, autosomal dominant neurodegenerative
disorder characterized by cognitive decline, motor dysfunction, and psychiatric disturbances …

Neurodegenerative diseases affect an increasing part of the population of modern societies,
burdening healthcare systems and causing immense suffering at the personal level. The …

Modeling cellular dynamics from single-cell RNA sequencing (scRNA-seq) data is critical for
understanding cell development and underlying gene regulatory relationships. Many current …

Regulatory proteins have evolved diverse repressor domains (RDs) to enable precise
context-specific repression of transcription. However, our understanding of how sequence …