Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

Functional aqueous droplet networks

MJ Booth, VR Schild, FG Downs, H Bayley - Molecular BioSystems, 2017 - pubs.rsc.org
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …

Air-stable droplet interface bilayers on oil-infused surfaces

JB Boreyko, G Polizos, PG Datskos… - Proceedings of the …, 2014 - National Acad Sciences
Droplet interface bilayers are versatile model membranes useful for synthetic biology and
biosensing; however, to date they have always been confined to fluid reservoirs. Here, we …

Constructing droplet interface bilayers from the contact of aqueous droplets in oil

S Leptihn, OK Castell, B Cronin, EH Lee, LCM Gross… - Nature protocols, 2013 - nature.com
We describe a protocol for forming an artificial lipid bilayer by contacting nanoliter aqueous
droplets in an oil solution in the presence of phospholipids. A lipid monolayer forms at each …

Challenges and opportunities in achieving the full potential of droplet interface bilayers

EB Stephenson, JL Korner, KS Elvira - Nature Chemistry, 2022 - nature.com
Abstract Model membranes can be used to elucidate the intricacies of the chemical
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …

Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks

Y Elani, AJ Demello, X Niu, O Ces - Lab on a Chip, 2012 - pubs.rsc.org
Droplet interface bilayer (DIB) networks have vast potential in the field of membrane
biophysics, synthetic biology, and functional bio-electronics. However a technological …

Hydrodynamic trap** for rapid assembly and in situ electrical characterization of droplet interface bilayer arrays

MA Nguyen, B Srijanto, CP Collier, ST Retterer… - Lab on a Chip, 2016 - pubs.rsc.org
The droplet interface bilayer (DIB) is a modular technique for assembling planar lipid
membranes between water droplets in oil. The DIB method thus provides a unique capability …

Characterizing the structure and interactions of model lipid membranes using electrophysiology

J El-Beyrouthy, E Freeman - Membranes, 2021 - mdpi.com
The cell membrane is a protective barrier whose configuration determines the exchange
both between intracellular and extracellular regions and within the cell itself. Consequently …

Intrinsic voltage offsets in memcapacitive biomembranes enable high-performance physical reservoir computing

AS Mohamed, A Dhungel, MS Hasan… - ACS Applied …, 2024 - ACS Publications
Reservoir computing is a brain-inspired machine learning framework for processing
temporal data by map** inputs into high-dimensional spaces. Physical reservoir …

Hair cell inspired mechanotransduction with a gel-supported, artificial lipid membrane

SA Sarles, JDW Madden, DJ Leo - Soft matter, 2011 - pubs.rsc.org
A gel-supported lipid bilayer formed at the base of an artificial hair is used as the
transduction element in an artificial, membrane-based hair cell sensor inspired by the …