Artificial cell membrane systems for biosensing applications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …
a cell or organelle. They also mediate signal transduction and transport of various molecules …
Functional aqueous droplet networks
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …
Air-stable droplet interface bilayers on oil-infused surfaces
Droplet interface bilayers are versatile model membranes useful for synthetic biology and
biosensing; however, to date they have always been confined to fluid reservoirs. Here, we …
biosensing; however, to date they have always been confined to fluid reservoirs. Here, we …
Constructing droplet interface bilayers from the contact of aqueous droplets in oil
We describe a protocol for forming an artificial lipid bilayer by contacting nanoliter aqueous
droplets in an oil solution in the presence of phospholipids. A lipid monolayer forms at each …
droplets in an oil solution in the presence of phospholipids. A lipid monolayer forms at each …
Challenges and opportunities in achieving the full potential of droplet interface bilayers
Abstract Model membranes can be used to elucidate the intricacies of the chemical
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …
Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks
Droplet interface bilayer (DIB) networks have vast potential in the field of membrane
biophysics, synthetic biology, and functional bio-electronics. However a technological …
biophysics, synthetic biology, and functional bio-electronics. However a technological …
Hydrodynamic trap** for rapid assembly and in situ electrical characterization of droplet interface bilayer arrays
The droplet interface bilayer (DIB) is a modular technique for assembling planar lipid
membranes between water droplets in oil. The DIB method thus provides a unique capability …
membranes between water droplets in oil. The DIB method thus provides a unique capability …
Characterizing the structure and interactions of model lipid membranes using electrophysiology
The cell membrane is a protective barrier whose configuration determines the exchange
both between intracellular and extracellular regions and within the cell itself. Consequently …
both between intracellular and extracellular regions and within the cell itself. Consequently …
Intrinsic voltage offsets in memcapacitive biomembranes enable high-performance physical reservoir computing
Reservoir computing is a brain-inspired machine learning framework for processing
temporal data by map** inputs into high-dimensional spaces. Physical reservoir …
temporal data by map** inputs into high-dimensional spaces. Physical reservoir …
Hair cell inspired mechanotransduction with a gel-supported, artificial lipid membrane
A gel-supported lipid bilayer formed at the base of an artificial hair is used as the
transduction element in an artificial, membrane-based hair cell sensor inspired by the …
transduction element in an artificial, membrane-based hair cell sensor inspired by the …