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Experimental methods and modeling techniques for description of cell population heterogeneity
RL Fernandes, M Nierychlo, L Lundin… - Biotechnology …, 2011 - Elsevier
With the continuous development, in the last decades, of analytical techniques providing
complex information at single cell level, the study of cell heterogeneity has been the focus of …
complex information at single cell level, the study of cell heterogeneity has been the focus of …
[HTML][HTML] History and evolution of modeling in biotechnology: modeling & simulation, application and hardware performance
P Noll, M Henkel - Computational and Structural Biotechnology Journal, 2020 - Elsevier
Biological systems are typically composed of highly interconnected subunits and possess an
inherent complexity that make monitoring, control and optimization of a bioprocess a …
inherent complexity that make monitoring, control and optimization of a bioprocess a …
Dissolved oxygen control of the activated sludge wastewater treatment process using model predictive control
Activated sludge wastewater treatment processes are difficult to be controlled because of
their complex and nonlinear behavior, however, the control of the dissolved oxygen level in …
their complex and nonlinear behavior, however, the control of the dissolved oxygen level in …
Model based control of a yeast fermentation bioreactor using optimally designed artificial neural networks
ZK Nagy - Chemical engineering journal, 2007 - Elsevier
Artificial Neural Networks (ANN) have been used for a wide variety of chemical applications
because of their ability to learn system features. This paper presents the use of feedforward …
because of their ability to learn system features. This paper presents the use of feedforward …
Deep reinforcement learning for the control of microbial co-cultures in bioreactors
NJ Treloar, AJH Fedorec, B Ingalls… - PLoS computational …, 2020 - journals.plos.org
Multi-species microbial communities are widespread in natural ecosystems. When
employed for biomanufacturing, engineered synthetic communities have shown increased …
employed for biomanufacturing, engineered synthetic communities have shown increased …
Active filtering of physiological motion in robotized surgery using predictive control
R Ginhoux, J Gangloff, M de Mathelin… - IEEE Transactions …, 2005 - ieeexplore.ieee.org
This work presents a predictive-control approach to active mechanical filtering of complex,
periodic motions of organs induced by respiration or heart beating in robotized surgery. Two …
periodic motions of organs induced by respiration or heart beating in robotized surgery. Two …
Model predictive control for wastewater treatment process with feedforward compensation
W Shen, X Chen, MN Pons, JP Corriou - Chemical Engineering Journal, 2009 - Elsevier
Being an optimizing technology, model predictive control (MPC) can now be found in a wide
variety of application fields. The main and most obvious control goal to be achieved in a …
variety of application fields. The main and most obvious control goal to be achieved in a …
Application of model predictive control to the BSM1 benchmark of wastewater treatment process
W Shen, X Chen, JP Corriou - Computers & Chemical Engineering, 2008 - Elsevier
Wastewater treatment processes are difficult to be controlled because of their complex and
nonlinear behavior. This paper applied model predictive control (MPC) to the Benchmark …
nonlinear behavior. This paper applied model predictive control (MPC) to the Benchmark …
General hybrid multizonal/CFD approach for bioreactor modeling
F Bezzo, S Macchietto, CC Pantelides - AIChE Journal, 2003 - Wiley Online Library
A critical issue in the modeling of aerobic bioreactors is the close interaction between fluid
flow and the biological reactions. In particular, shear rate has a large effect on the broth …
flow and the biological reactions. In particular, shear rate has a large effect on the broth …
Dynamic modeling of microbial cell populations
MA Henson - Current opinion in biotechnology, 2003 - Elsevier
Microbial cultures are comprised of heterogeneous cells that differ according to their size
and intracellular concentrations of DNA, proteins and other constituents. Recent advances …
and intracellular concentrations of DNA, proteins and other constituents. Recent advances …