Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Tryptophan (Trp) metabolism primarily involves the kynurenine, 5-hydroxytryptamine, and
indole pathways. A variety of bioactive compounds produced via Trp metabolism can …

O eixo microbiota-intestino-cérebro foi recentemente reconhecido como um modulador
chave de distúrbios neurológicos, incluindo o Transtorno do Espectro Autista (TEA) …

Preclinical evidence has firmly established bidirectional interactions among the brain, the
gut, and the gut microbiome. Candidate signaling molecules and at least three …

Emerging evidence indicates that the gut microbiota play a crucial role in the bidirectional
communication between the gut and the brain suggesting that the gut microbes may shape …

Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Emerging evidence indicates that gut microbiota is important in the regulation of brain
activity and cognitive functions. Microbes mediate communication among the metabolic …

The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

The human gut microbiota has received considerable interest in the recent years and our
knowledge of the inhabitant species and their potential applications is increased particularly …