Traditional therapeutic approaches such as chemotherapy and radiation therapy have
burdened cancer patients with onerous physical and psychological challenges …

In principle, proton therapy offers a substantial clinical advantage over conventional photon
therapy. This is because of the unique depth-dose characteristics of protons, which can be …

The original rationale for proton therapy was its highly conformal depth‐dose distributions
compared to photons, which allow greater sparing of normal tissues and escalation of tumor …

The introduction of advanced techniques and technology in radiotherapy has greatly
improved our ability to deliver highly conformal tumor doses while minimizing the dose to …

From background physics and biological models to the latest imaging and treatment
modalities, the Handbook of Radiotherapy Physics: Theory and Practice covers all …

The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Purpose. To develop and disseminate a report aimed primarily at practicing radiation
oncology physicians and medical physicists that describes the current state-of-the-art of …

Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising
innovations over the past decade in the field of radiation oncology, with the potential to …

The characteristic Bragg peak of protons or heavy ions provides a good localization of dose
in three dimensions. Through their ability to deliver laterally and distally shaped …

Immunotherapy is radically changing the clinical management of patients affected by an
increasingly wide array of tumours. However, not all patients achieve long-term clinical …