[HTML][HTML] Herpes virus reactivation in astronauts during spaceflight and its application on earth

BV Rooney, BE Crucian, DL Pierson… - Frontiers in …, 2019 - frontiersin.org
Latent herpes virus reactivation has been demonstrated in astronauts during shuttle (10–16
days) and International Space Station (≥ 180 days) flights. Following reactivation, viruses …

Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients

L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

Immunosenescence and cytomegalovirus: exploring their connection in the context of aging, health, and disease

L Müller, S Di Benedetto - International Journal of Molecular Sciences, 2024 - mdpi.com
Aging induces numerous physiological alterations, with immunosenescence emerging as a
pivotal factor. This phenomenon has attracted both researchers and clinicians, prompting …

HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions

CS Nelson, T Huffman, JA Jenks… - Proceedings of the …, 2018 - pnas.org
Human cytomegalovirus (HCMV) is the most common congenital infection worldwide,
frequently causing hearing loss and brain damage in afflicted infants. A vaccine to prevent …

[HTML][HTML] The human Papillomavirus twilight zone–Latency, immune control and subclinical infection

J Doorbar - Tumour Virus Research, 2023 - Elsevier
The incorporation of HPV DNA testing into cervical screening programs has shown that
many HPV-positive women are cytologically normal, with HPV-positivity fluctuating …

Cytomegalovirus anterior uveitis: clinical manifestations, diagnosis, treatment, and immunological mechanisms

J Zhang, K Kamoi, Y Zong, M Yang, K Ohno-Matsui - Viruses, 2023 - mdpi.com
Little is known regarding anterior uveitis (AU), the most common ocular disease associated
with cytomegalovirus (CMV) infection in immunocompetent populations. CMV AU is highly …

Latent cytomegalovirus (CMV) infection does not detrimentally alter T cell responses in the healthy old, but increased latent CMV carriage is related to expanded CMV …

SE Jackson, GX Sedikides, G Okecha… - Frontiers in …, 2017 - frontiersin.org
Human cytomegalovirus (HCMV) primary infection and periodic reactivation of latent virus is
generally well controlled by T-cell responses in healthy people. In older donors, overt HCMV …

The CD4+ T cell response to human cytomegalovirus in healthy and immunocompromised people

EY Lim, SE Jackson, MR Wills - Frontiers in cellular and infection …, 2020 - frontiersin.org
While CD8+ T cells specific for human cytomegalovirus (HCMV) have been extensively
studied in both healthy HCMV seropositive carriers and patients undergoing …

Dual inhibition of innate immunity and apoptosis by human cytomegalovirus protein UL37x1 enables efficient virus replication

Y Ren, A Wang, D Wu, C Wang, M Huang, X **ong… - Nature …, 2022 - nature.com
Immune evasion and inhibition of apoptosis are required for successful virus infection.
However, inhibition of apoptosis can increase antiviral immune responses, which can then …

A practical review of cytomegalovirus in gastroenterology and hepatology

AY Fakhreddine, CT Frenette… - … research and practice, 2019 - Wiley Online Library
Human cytomegalovirus (CMV) is a ubiquitous Herpesviridae virus with a wide spectrum of
pathology in humans. Host immunity is a major determinant of the clinical manifestation of …