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Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
Evolution of prefrontal cortex
TM Preuss, SP Wise - Neuropsychopharmacology, 2022 - nature.com
Subdivisions of the prefrontal cortex (PFC) evolved at different times. Agranular parts of the
PFC emerged in early mammals, and rodents, primates, and other modern mammals share …
PFC emerged in early mammals, and rodents, primates, and other modern mammals share …
The evolution of gene expression levels in mammalian organs
Abstract Changes in gene expression are thought to underlie many of the phenotypic
differences between species. However, large-scale analyses of gene expression evolution …
differences between species. However, large-scale analyses of gene expression evolution …
Detecting signatures of selection on gene expression
A substantial amount of phenotypic diversity results from changes in gene expression levels
and patterns. Understanding how the transcriptome evolves is therefore a key priority in …
and patterns. Understanding how the transcriptome evolves is therefore a key priority in …
Genomic insights that advance the species definition for prokaryotes
To help advance the species definition for prokaryotes, we have compared the gene content
of 70 closely related and fully sequenced bacterial genomes to identify whether species …
of 70 closely related and fully sequenced bacterial genomes to identify whether species …
[HTML][HTML] The mystery of language evolution
Understanding the evolution of language requires evidence regarding origins and
processes that led to change. In the last 40 years, there has been an explosion of research …
processes that led to change. In the last 40 years, there has been an explosion of research …
Comparative studies of gene expression and the evolution of gene regulation
The hypothesis that differences in gene regulation have an important role in speciation and
adaptation is more than 40 years old. With the advent of new sequencing technologies, we …
adaptation is more than 40 years old. With the advent of new sequencing technologies, we …
The evolution of human language
W Wildgen - 2004 - torrossa.com
Why should one believe that evolutionary aspects could bring new insights into linguistics,
semiotics, and cognitive science? Saussure dismissed historical, and with them …
semiotics, and cognitive science? Saussure dismissed historical, and with them …
Comparative single-cell transcriptomic analysis of primate brains highlights human-specific regulatory evolution
Enhanced cognitive function in humans is hypothesized to result from cortical expansion
and increased cellular diversity. However, the mechanisms that drive these phenotypic …
and increased cellular diversity. However, the mechanisms that drive these phenotypic …
The evolutionary significance of cis-regulatory mutations
GA Wray - Nature Reviews Genetics, 2007 - nature.com
For decades, evolutionary biologists have argued that changes in cis-regulatory sequences
constitute an important part of the genetic basis for adaptation. Although originally based on …
constitute an important part of the genetic basis for adaptation. Although originally based on …