Protocells: Milestones and recent advances

I Gözen, ES Köksal, I Põldsalu, L Xue, K Spustova… - Small, 2022 - Wiley Online Library
The origin of life is still one of humankind's great mysteries. At the transition between
nonliving and living matter, protocells, initially featureless aggregates of abiotic matter, gain …

Remodeling of membrane shape and topology by curvature elasticity and membrane tension

R Lipowsky - Advanced Biology, 2022 - Wiley Online Library
Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

Division in synthetic cells

MY Chang, H Ariyama, WTS Huck… - Chemical Society …, 2023 - pubs.rsc.org
The bottom-up construction of a living cell using non-living materials represents a grand
challenge in science and technology. Reproduction of cells into similar offspring is key to …

Dynamics and equilibration mechanisms in block copolymer particles

TP Lodge, CL Seitzinger, SC Seeger, S Yang… - ACS polymers …, 2022 - ACS Publications
Self-assembly of block copolymers into interesting and useful nanostructures, in both
solution and bulk, is a vibrant research arena. While much attention has been paid to …

Different pathways for engulfment and endocytosis of liquid droplets by nanovesicles

R Ghosh, V Satarifard, R Lipowsky - Nature Communications, 2023 - nature.com
During endocytosis of nanoparticles by cells, the cellular membranes engulf the particles,
thereby forming a closed membrane neck that subsequently undergoes fission. For solid …

Membrane fission via transmembrane contact

RKW Spencer, I Santos-Pérez… - Nature …, 2024 - nature.com
Division of intracellular organelles often correlates with additional membrane wrap**, eg,
by the endoplasmic reticulum or the outer mitochondrial membrane. Such wrap** plays a …

[HTML][HTML] Multispherical shapes of vesicles highlight the curvature elasticity of biomembranes

R Lipowsky - Advances in Colloid and Interface Science, 2022 - Elsevier
Giant lipid vesicles form unusual multispherical or “multi-balloon” shapes consisting of
several spheres that are connected by membrane necks. Such multispherical shapes have …

Leaflet tensions control the spatio-temporal remodeling of lipid bilayers and nanovesicles

R Lipowsky, R Ghosh, V Satarifard, A Sreekumari… - Biomolecules, 2023 - mdpi.com
Biological and biomimetic membranes are based on lipid bilayers, which consist of two
monolayers or leaflets. To avoid bilayer edges, which form when the hydrophobic core of …

Activation energy and force fields during topological transitions of fluid lipid vesicles

M Bottacchiari, M Gallo, M Bussoletti… - Communications …, 2022 - nature.com
Topological transitions of fluid lipid membranes are fundamental processes for cell life. For
example, they are required for endo-and exocytosis or to enable neurotransmitters to cross …

Remodeling of biomembranes and vesicles by adhesion of condensate droplets

R Lipowsky - Membranes, 2023 - mdpi.com
Condensate droplets are formed in aqueous solutions of macromolecules that undergo
phase separation into two liquid phases. A well-studied example are solutions of the two …