Nanopore-based technologies beyond DNA sequencing

YL Ying, ZL Hu, S Zhang, Y Qing, A Fragasso… - Nature …, 2022 - nature.com
Inspired by the biological processes of molecular recognition and transportation across
membranes, nanopore techniques have evolved in recent decades as ultrasensitive …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum

S Cai, T Pataillot-Meakin, A Shibakawa, R Ren… - Nature …, 2021 - nature.com
MicroRNAs (miRNAs) play essential roles in post-transcriptional gene expression and are
also found freely circulating in bodily fluids such as blood. Dysregulated miRNA signatures …

Bioinspired smart asymmetric nanochannel membranes

Z Zhang, L Wen, L Jiang - Chemical Society Reviews, 2018 - pubs.rsc.org
Bioinspired smart asymmetric nanochannel membranes (BSANM) have been explored
extensively to achieve the delicate ionic transport functions comparable to those of living …

Ion/molecule transportation in nanopores and nanochannels: from critical principles to diverse functions

Z Zhu, D Wang, Y Tian, L Jiang - Journal of the American …, 2019 - ACS Publications
Nanopores and nanochannels are ubiquitous, from biological systems to various artificial
materials. Taking advantage of size confinement and tailoring the interior components …

Track‐etched nanopore/membrane: from fundamental to applications

T Ma, JM Janot, S Balme - Small Methods, 2020 - Wiley Online Library
Biomimetic and bio‐inspired membranes draw great attention and generate extensive efforts
to solve environmental, health, and energy issues. In this field, track‐etched membranes …

Protein identification by nanopore peptide profiling

FLR Lucas, RCA Versloot, L Yakovlieva… - Nature …, 2021 - nature.com
Nanopores are single-molecule sensors used in nucleic acid analysis, whereas their
applicability towards full protein identification has yet to be demonstrated. Here, we show …

Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution

J Jiang, MY Li, XY Wu, YL Ying, HX Han, YT Long - Nature Chemistry, 2023 - nature.com
The discovery of crosstalk effects on the renin–angiotensin system (RAS) is limited by the
lack of approaches to quantitatively monitor, in real time, multiple components with subtle …

Nanopore sensing

W Shi, AK Friedman, LA Baker - Analytical chemistry, 2017 - ACS Publications
Scope of the Review. Herein, we provide an up-to-date overview of the field of nanopore
sensing with emphases placed on the advances made in the most recent two years (2014 …