Recent advances in 1, 2, 4‐triazole scaffolds as antiviral agents

SA El‐Sebaey - ChemistrySelect, 2020 - Wiley Online Library
In recent years, severe viral infections have emerged, and antiviral chemotherapeutic agents
are not adequately effective in curing these infections, leading to serious human diseases …

Exploring the chemistry and therapeutic potential of triazoles: a comprehensive literature review

A Jain, P Piplani - Mini Reviews in Medicinal Chemistry, 2019 - ingentaconnect.com
Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological
properties, which could play a major role in the common mechanisms associated with …

Design and antiproliferative and antioxidant activities of furan-based thiosemicarbazides and 1, 2, 4-triazoles: their structure-activity relationship and SwissADME …

Y Sicak - Medicinal Chemistry Research, 2021 - Springer
Due to the limited number of drugs in current clinical use, the diverse biological applications
of furan have encouraged the preparation of a wide variety of thiosemicarbazide and triazole …

Antiviral activity of 1, 2, 4-triazole derivatives (microreview)

NV Simurova, OI Maiboroda - Chemistry of heterocyclic compounds, 2021 - Springer
Antiviral activity of 1,2,4-triazole derivatives (microreview) | Chemistry of Heterocyclic
Compounds Skip to main content Advertisement Springer Nature Link Account Menu Find a …

Biological activity and molecular docking studies of some N‐phenylsulfonamides against cholinesterases and carbonic anhydrase isoenzymes

E Başaran, R Çakmak, M Şentürk… - Journal of Molecular …, 2022 - Wiley Online Library
In this research, a series of N‐phenylsulfonamide derivatives (1‐12) were designed,
synthesized, and investigated for their inhibitory potencies against carbonic anhydrase …

Recent advances in triazole-benzenesulfonamide hybrids and their biological activities

Chander, Monika, PK Sharma, S Ram - Medicinal Chemistry Research, 2023 - Springer
Hybridization is the process of fusion of two or more existing moieties to make a single
molecule. Triazoles and benzenesulfonamides are the useful pharmacological agents …

Recent advances in biological active sulfonamide based hybrid compounds part B: Two-component sulfonamide hybrids

S Ghomashi, R Ghomashi, H Aghaei… - Current Medicinal …, 2023 - benthamdirect.com
Sulfonamide compounds, also known as sulfa drugs, are a significant class of synthetic
bacteriostatic antimicrobials and were the primary source of therapy against bacterial …

Chiral thioureas containing naphthalene moiety as selective butyrylcholinesterase inhibitors: Design, synthesis, cholinesterase inhibition activity and molecular …

A Karaküçük-İyidoğan, Y Sıcak, DB Uysal… - Journal of Molecular …, 2025 - Elsevier
Butyrylcholinesterase (BChE), which plays a role in the regulation of acetylcholine (ACh) as
well as cholinergic type neurotransmission, also has non-cholinergic functions such as …

[HTML][HTML] Multi-omics studies towards novel modulators of influenza A virus–host interaction

S Söderholm, Y Fu, L Gaelings, S Belanov, L Yetukuri… - Viruses, 2016 - mdpi.com
Human influenza A viruses (IAVs) cause global pandemics and epidemics. These viruses
evolve rapidly, making current treatment options ineffective. To identify novel modulators of …

Synthesis of novel chiral metal complexes derived from chiral thiosemicarbazide ligands as potential antioxidant agents

E Başaran, Y Sıcak, HG Sogukomerogullari… - Chirality, 2019 - Wiley Online Library
Two new chiral thiosemicarbazide ligands and their Cu (II), Ni (II), Pd (II), and Zn (II)
complexes were synthesized and characterized by nuclear magnetic resonance (NMR)(only …