The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2,
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …

Nuclear mRNA transcripts acquire a protein coat composed of cap-and RNA-binding
proteins that allow nuclear export and dictate the functional program of cytoplasmic mRNAs …

Post-transcriptional processes have a central role in the regulation of eukaryotic gene
expression. Although it has been known for a long time that these processes are functionally …

The importance of subcellular mRNA localization is well established, but the underlying
mechanisms mostly remain an enigma. Early studies suggested that specific mRNA …

Key early features of amyotrophic lateral sclerosis (ALS) are denervation of neuromuscular
junctions and axonal degeneration. Motor neuron homeostasis relies on local translation …

RNA‐binding proteins (RBPs) mediate the localization, stability, and translation of the target
transcripts and fine‐tune the physiological functions of the proteins encoded. The insulin …

Selected long noncoding RNAs (lncRNAs) have been shown to play important roles in
carcinogenesis. Although the cellular functions of these transcripts can be diverse, many …

Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

Oncofetal RNA‐binding IMPs have been implicated in mRNA localization, nuclear export,
turnover and translational control. To depict the cellular actions of IMPs, we performed a loss …

IMPs, also known as insulin-like growth factor 2 (IGF2) messenger RNA (mRNA)-binding
proteins (IGF2BPs), are highly conserved oncofetal RNA-binding proteins (RBPs) that …