Biointerface design for vertical nanoprobes

R Elnathan, MG Barbato, X Guo, A Mariano… - Nature Reviews …, 2022 - nature.com
Biointerfaces mediate safe and efficient cell manipulation, which is essential for biomedical
innovations in advanced therapies and diagnostics. The biointerface established by vertical …

Piezoelectric MEMS—Evolution from sensing technology to diversified applications in the 5G/Internet of Things (IoT) era

X Le, Q Shi, P Vachon, EJ Ng… - Journal of Micromechanics …, 2021 - iopscience.iop.org
The rapid development of the fifth-generation mobile networks (5G) and Internet of Things
(IoT) is inseparable from a large number of miniature, low-cost, and low-power sensors and …

The 2019 surface acoustic waves roadmap

P Delsing, AN Cleland, MJA Schuetz… - Journal of Physics D …, 2019 - iopscience.iop.org
Today, surface acoustic waves (SAWs) and bulk acoustic waves are already two of the very
few phononic technologies of industrial relevance and can been found in a myriad of …

[HTML][HTML] A review of emerging physical transfection methods for CRISPR/Cas9-mediated gene editing

AK Fajrial, QQ He, NI Wirusanti, JE Slansky, X Ding - Theranostics, 2020 - ncbi.nlm.nih.gov
Gene editing is a versatile technique in biomedicine that promotes fundamental research as
well as clinical therapy. The development of Clustered Regularly Interspaced Short …

High frequency acoustic cell stimulation promotes exosome generation regulated by a calcium-dependent mechanism

LA Ambattu, S Ramesan, C Dekiwadia… - Communications …, 2020 - nature.com
Exosomes are promising disease diagnostic markers and drug delivery vehicles, although
their use in practice is limited by insufficient homogeneous quantities that can be produced …

Acoustofluidics–changing paradigm in tissue engineering, therapeutics development, and biosensing

R Rasouli, KM Villegas, M Tabrizian - Lab on a Chip, 2023 - pubs.rsc.org
For more than 70 years, acoustic waves have been used to screen, diagnose, and treat
patients in hundreds of medical devices. The biocompatible nature of acoustic waves, their …

Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells

JN Belling, LK Heidenreich, Z Tian… - Proceedings of the …, 2020 - National Acad Sciences
Advances in gene editing are leading to new medical interventions where patients' own cells
are used for stem cell therapies and immunotherapies. One of the key limitations to …

Microfluidic and nanofluidic intracellular delivery

J Hur, AJ Chung - Advanced Science, 2021 - Wiley Online Library
Innate cell function can be artificially engineered and reprogrammed by introducing
biomolecules, such as DNAs, RNAs, plasmid DNAs, proteins, or nanomaterials, into the …

Electroactive nanoinjection platform for intracellular delivery and gene silencing

AR Shokouhi, Y Chen, HZ Yoh, T Murayama… - Journal of …, 2023 - Springer
Background Nanoinjection—the process of intracellular delivery using vertically configured
nanostructures—is a physical route that efficiently negotiates the plasma membrane, with …

Recent advances in microfluidics for drug screening

J Sun, AR Warden, X Ding - Biomicrofluidics, 2019 - pubs.aip.org
With ever increasing drug resistance and emergence of new diseases, demand for new drug
development is at an unprecedented urgency. This fact has led to extensive recent efforts to …