Narcolepsy with cataplexy
Narcolepsy with cataplexy is a disabling sleep disorder affecting 0· 02% of adults worldwide.
It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone …
It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone …
Modafinil: a review of neurochemical actions and effects on cognition
Abstract Modafinil (2-[(Diphenylmethyl) sulfinyl] acetamide, Provigil) is an FDA-approved
medication with wake-promoting properties. Pre-clinical studies of modafinil suggest a …
medication with wake-promoting properties. Pre-clinical studies of modafinil suggest a …
Dorsal raphe dopamine neurons modulate arousal and promote wakefulness by salient stimuli
JR Cho, JB Treweek, JE Robinson, C **_neuronal_and_chemical_substrates/links/5ae334530f7e9b28594ac37d/From-waking-to-slee**-neuronal-and-chemical-substrates.pdf" data-clk="hl=en&sa=T&oi=gga&ct=gga&cd=4&d=17568334064173814143&ei=UlKsZ9eKF-zDieoP2tyjoAc" data-clk-atid="f5F5FsBCz_MJ" target="_blank">[PDF] researchgate.net
From waking to slee**: neuronal and chemical substrates
BE Jones - Trends in pharmacological sciences, 2005 - cell.com
Multiple arousal systems maintain waking through the actions of chemical neurotransmitters
that are released from broadly distributed nerve terminals when the neurons fire. Among …
that are released from broadly distributed nerve terminals when the neurons fire. Among …
The neuropsychiatry of impulsivity
Neuropsychological assessment shows great promise in the investigation of impulsivity and
its brain substrates. These results support a key role for response inhibition, a function linked …
its brain substrates. These results support a key role for response inhibition, a function linked …
Hypothalamic arousal regions are activated during modafinil-induced wakefulness
TE Scammell, IV Estabrooke, MT McCarthy… - Journal of …, 2000 - Soc Neuroscience
Modafinil is an increasingly popular wake-promoting drug used for the treatment of
narcolepsy, but its precise mechanism of action is unknown. To determine potential …
narcolepsy, but its precise mechanism of action is unknown. To determine potential …
Noradrenergic modulation of arousal
CW Berridge - Brain research reviews, 2008 - Elsevier
Through a highly divergent efferent projection system, the locus coeruleus-noradrenergic
system supplies norepinephrine throughout the central nervous system. State-dependent …
system supplies norepinephrine throughout the central nervous system. State-dependent …
Dopaminergic modulation of arousal in Drosophila
Background: Arousal levels in the brain set thresholds for behavior, from simple to complex.
The mechanistic underpinnings of the various phenomena comprising arousal, however, are …
The mechanistic underpinnings of the various phenomena comprising arousal, however, are …
A systematic review of modafinil: potential clinical uses and mechanisms of action
JS Ballon, D Feifel - Journal of clinical Psychiatry, 2006 - psychiatrist.com
Background: Modafinil is a novel wakepromoting agent that has US Food and Drug
Administration approval for narcolepsy and shift work sleep disorder and as adjunctive …
Administration approval for narcolepsy and shift work sleep disorder and as adjunctive …