Endogenous photosensitizers in human skin

EL Bastos, FH Quina, MS Baptista - Chemical Reviews, 2023 - ACS Publications
Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

Singlet oxygen photophysics: from liquid solvents to mammalian cells

M Bregnhøj, F Thorning, PR Ogilby - Chemical Reviews, 2024 - ACS Publications
Molecular oxygen, O2, has long provided a cornerstone for studies in chemistry, physics,
and biology. Although the triplet ground state, O2 (X3Σg–), has garnered much attention, the …

[HTML][HTML] How does the skin sense sun light? An integrative view of light sensing molecules

LVM de Assis, PN Tonolli, MN Moraes… - … of Photochemistry and …, 2021 - Elsevier
The consensus on the effects of excessive sun exposure on human health has long
emphasized the negative effects of solar UV radiation. Nevertheless, although UV radiation …

A light life together: photosensing in the plant microbiota

A Losi, W Gärtner - Photochemical & Photobiological Sciences, 2021 - Springer
Bacteria and fungi of the plant microbiota can be phytopathogens, parasites or symbionts
that establish mutually advantageous relationships with plants. They are often rich in …

Engineering of LOV-domains for their use as protein tags

SG Kaya, A Hovan, MW Fraaije - Archives of Biochemistry and Biophysics, 2024 - Elsevier
Abstract Light-Oxygen-Voltage (LOV) domains are the protein-based light switches used in
nature to trigger and regulate various processes. They allow light signals to be converted …

Tailored flavoproteins acting as light-driven spin machines pump nuclear hyperpolarization

Y Ding, AS Kiryutin, Z Zhao, QZ Xu, KH Zhao, P Kurle… - Scientific reports, 2020 - nature.com
The solid-state photo-chemically induced dynamic nuclear polarization (photo-CIDNP) effect
generates non-Boltzmann nuclear spin magnetization, referred to as hyperpolarization …

Photosensitizing proteins for antibacterial photodynamic inactivation

C Hally, P Delcanale, S Nonell… - Translational …, 2020 - Wiley Online Library
We review recent applications of water‐soluble proteins as carriers for photosensitizing
molecules in antimicrobial photodynamic therapy (aPDT). The low water solubility of …

[HTML][HTML] Photoinduced bleaching in an efficient singlet oxygen photosensitizing protein: Identifying a culprit in the flavin-binding LOV-based protein SOPP3

DJ Mogensen, M Etzerodt, PR Ogilby - Journal of Photochemistry and …, 2022 - Elsevier
Abstract Light-oxygen-voltage (LOV) proteins that bind flavin mononucleotide (FMN) have
received attention as optogenetic systems that can photosensitize the production of singlet …

Effects of Proline Substitutions on the Thermostable LOV Domain from Chloroflexus aggregans

A Remeeva, VV Nazarenko, IM Goncharov, A Yudenko… - Crystals, 2020 - mdpi.com
Light-oxygen-voltage (LOV) domains are ubiquitous photosensory modules found in
proteins from bacteria, archaea and eukaryotes. Engineered versions of LOV domains have …

Stable Transfection of the Singlet Oxygen Photosensitizing Protein SOPP3: Examining Aspects of Intracellular Behavior

DJ Mogensen, M Westberg… - Photochemistry and …, 2021 - Wiley Online Library
Protein‐encased chromophores that photosensitize the production of reactive oxygen
species, ROS, have been the center of recent activity in studies of oxidative stress. One …