Toxicity of metal-based nanoparticles: Challenges in the nano era

N Zhang, G **ong, Z Liu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
With the rapid progress of nanotechnology, various nanoparticles (NPs) have been
applicated in our daily life. In the field of nanotechnology, metal-based NPs are an important …

The toxicity of nanoparticles and their interaction with cells: an in vitro metabolomic perspective

M Awashra, P Młynarz - Nanoscale Advances, 2023 - pubs.rsc.org
Nowadays, nanomaterials (NMs) are widely present in daily life due to their significant
benefits, as demonstrated by their application in many fields such as biomedicine …

[HTML][HTML] Nanotoxicology and nanosafety: Safety-by-design and testing at a glance

A Zielińska, B Costa, MV Ferreira, D Miguéis… - International journal of …, 2020 - mdpi.com
This review offers a systematic discussion about nanotoxicology and nanosafety associated
with nanomaterials during manufacture and further biomedical applications. A detailed …

Understanding nanomaterial–liver interactions to facilitate the development of safer nanoapplications

J Li, C Chen, T **a - Advanced Materials, 2022 - Wiley Online Library
Nanomaterials (NMs) are widely used in commercial and medical products, such as
cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal …

Maternal exposure to polystyrene nanoparticles retarded fetal growth and triggered metabolic disorders of placenta and fetus in mice

G Chen, S **ong, Q **g, CAM van Gestel… - Science of The Total …, 2023 - Elsevier
Microplastics can enter the human body via direct body contact or the food chain, increasing
the likelihood of adverse impacts on pregnancy and fetal development. We investigated the …

Critical challenges and advances in recombinant adeno‐associated virus (rAAV) biomanufacturing

Q Fu, A Polanco, YS Lee, S Yoon - Biotechnology and …, 2023 - Wiley Online Library
Gene therapy is a promising therapeutic approach for genetic and acquired diseases
nowadays. Among DNA delivery vectors, recombinant adeno‐associated virus (rAAV) is one …

[HTML][HTML] Metabolome changes in cerebral ischemia

TH Shin, DY Lee, S Basith, B Manavalan, MJ Paik… - Cells, 2020 - mdpi.com
Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

Investigating the ecological implications of nanomaterials: Unveiling plants' notable responses to nano-pollution

E Gayathiri, P Prakash, S Pandiaraj… - Plant Physiology and …, 2024 - Elsevier
The rapid advancement of nanotechnology has led to unprecedented innovations; however,
it is crucial to analyze its environmental impacts carefully. This review thoroughly examines …

Mechanistic insights into the biological effects of engineered nanomaterials: a focus on gold nanoparticles

NHA Nguyen, P Falagan-Lotsch - International Journal of Molecular …, 2023 - mdpi.com
Nanotechnology has great potential to significantly advance the biomedical field for the
benefit of human health. However, the limited understanding of nano–bio interactions …

Metabolomics reveals the mechanism of polyethylene microplastic toxicity to Daphnia magna

P Wang, QQ Li, J Hui, QQ **ang, H Yan, LQ Chen - Chemosphere, 2022 - Elsevier
Microplastic exposure leads to various toxic effects in Daphnia magna; however, the effects
of microplastics on the metabolic processes in D. magna and the corresponding molecular …