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Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
[HTML][HTML] Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
Hair loss, or alopecia, is associated with several psychosocial and medical comorbidities,
and it remains an economic burden to individuals and the society. Alopecia is attributable to …
and it remains an economic burden to individuals and the society. Alopecia is attributable to …
A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential
Y Petrenko, I Vackova, K Kekulova, M Chudickova… - Scientific reports, 2020 - nature.com
Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …
[HTML][HTML] Manufacturing of human extracellular vesicle-based therapeutics for clinical use
M Gimona, K Pachler, S Laner-Plamberger… - International journal of …, 2017 - mdpi.com
Extracellular vesicles (EVs) derived from stem and progenitor cells may have therapeutic
effects comparable to their parental cells and are considered promising agents for the …
effects comparable to their parental cells and are considered promising agents for the …
Stem cell-derived exosomes: a new strategy of neurodegenerative disease treatment
Short-term symptomatic treatment and dose-dependent side effects of pharmacological
treatment for neurodegenerative diseases have forced the medical community to seek an …
treatment for neurodegenerative diseases have forced the medical community to seek an …
FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson's disease via m6A-dependent regulation …
Y Geng, X Long, Y Zhang, Y Wang, G You… - Journal of Translational …, 2023 - Springer
Background Parkinson's disease (PD), characterized by the progressive loss of
dopaminergic neurons in the substantia nigra and striatum of brain, seriously threatens …
dopaminergic neurons in the substantia nigra and striatum of brain, seriously threatens …
[HTML][HTML] Mesenchymal stem cell secretome and extracellular vesicles for neurodegenerative diseases: Risk-benefit profile and next steps for the market access
Neurodegenerative diseases represent a growing burden on healthcare systems worldwide.
Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …
Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their …
Dental pulp stem cell-derived secretome and its regenerative potential
JK Bar, A Lis-Nawara, PG Grelewski - International journal of molecular …, 2021 - mdpi.com
The therapeutic potential of the dental pulp stem (DSC) cell-derived secretome, consisting of
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
various biomolecules, is undergoing intense research. Despite promising in vitro and in vivo …
Conditioned media derived from mesenchymal stem cell cultures: The next generation for regenerative medicine
TNA Gunawardena, MT Rahman… - Journal of tissue …, 2019 - Wiley Online Library
Recent studies suggest that the main driving force behind the therapeutic activity observed
in mesenchymal stem cells (MSCs) are the paracrine factors secreted by these cells. These …
in mesenchymal stem cells (MSCs) are the paracrine factors secreted by these cells. These …