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Aging, inflammation and the environment
The aging process is driven by interrelated mechanisms that lead to the emergence of
characteristic phenotypes that include changes in body composition, energy production and …
characteristic phenotypes that include changes in body composition, energy production and …
The energetic brain–A review from students to students
The past 20 years have resulted in unprecedented progress in understanding brain energy
metabolism and its role in health and disease. In this review, which was initiated at the 14th …
metabolism and its role in health and disease. In this review, which was initiated at the 14th …
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition
All women undergo the menopause transition (MT), a neuro-endocrinological process that
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …
impacts aging trajectories of multiple organ systems including brain. The MT occurs over …
In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences
NAD is an essential metabolite that exists in NAD+ or NADH form in all living cells. Despite
its critical roles in regulating mitochondrial energy production through the NAD+/NADH …
its critical roles in regulating mitochondrial energy production through the NAD+/NADH …
Astrocyte glycogen and lactate: New insights into learning and memory mechanisms
Memory, the ability to retain learned information, is necessary for survival. Thus far,
molecular and cellular investigations of memory formation and storage have mainly focused …
molecular and cellular investigations of memory formation and storage have mainly focused …
Schizophrenia: a disorder of broken brain bioenergetics
A substantial and diverse body of literature suggests that the pathophysiology of
schizophrenia is related to deficits of bioenergetic function. While antipsychotics are an …
schizophrenia is related to deficits of bioenergetic function. While antipsychotics are an …
[کتاب][B] The matter of history: How things create the past
TJ LeCain - 2017 - books.google.com
New insights into the microbiome, epigenetics, and cognition are radically challenging our
very idea of what it means to be'human', while an explosion of neo-materialist thinking in the …
very idea of what it means to be'human', while an explosion of neo-materialist thinking in the …
Broken detailed balance and entropy production in the human brain
Living systems break detailed balance at small scales, consuming energy and producing
entropy in the environment to perform molecular and cellular functions. However, it remains …
entropy in the environment to perform molecular and cellular functions. However, it remains …
Exploring early human brain development with structural and physiological neuroimaging
Early brain development, from the embryonic period to infancy, is characterized by rapid
structural and functional changes. These changes can be studied using structural and …
structural and functional changes. These changes can be studied using structural and …
Focusing on mitochondria in the brain: from biology to therapeutics
N Song, S Mei, X Wang, G Hu, M Lu - Translational neurodegeneration, 2024 - Springer
Mitochondria have multiple functions such as supplying energy, regulating the redox status,
and producing proteins encoded by an independent genome. They are closely related to the …
and producing proteins encoded by an independent genome. They are closely related to the …