Damage to any tissue triggers a cascade of events that leads to rapid repair of the wound–if
the tissue is skin, then repair involves re-epithelialization, formation of granulation tissue and …

Brain endothelial cells are unique among endothelial cells in that they express apical
junctional complexes, including tight junctions, which quite resemble epithelial tight …

Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …

Current evidence supports that inflammation is a major driving force underlying the initiation
of coronary plaques, their unstable progression, and eventual disruption; patients with a …

The pattern recognition receptor, RAGE (receptor for advanced glycation endproducts),
propagates cellular dysfunction in several inflammatory disorders and diabetes. Here we …

Junctional adhesion molecules (JAMs) of the immunoglobulin superfamily are important in
the control of vascular permeability and leukocyte transmigration across endothelial-cell …

In recent years, transfusion‐related acute lung injury (TRALI) has developed from an almost
unknown transfusion reaction to the most common cause of transfusion‐related major …

Junctional adhesion molecules are a family of glycoproteins characterised by two
immunoglobulin folds (VH-and C2-type) in the extracellular domain. Junctional adhesion …

Migration of leukocytes into tissue is a key element of innate and adaptive immunity. While
the capturing of leukocytes to the blood vessel wall is well understood, little is known about …

Increasing reports on epidemiological, diagnostic, and clinical studies suggest that
dysfunction of the inflammatory reaction results in chronic illnesses such as cancer, arthritis …