Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …

Antibiotic resistance is one of the greatest challenges of the twenty-first century. However,
the increasing understanding of bacterial pathogenesis and intercellular communication has …

Like for all microbes, the goal of every pathogen is to survive and replicate. However, to
overcome the formidable defenses of their hosts, pathogens are also endowed with traits …

All organisms must sense and respond to their external environments, and this signal
transduction often involves second messengers such as cyclic nucleotides. One such …

The public view on antibiotics as reliable medicines changed when reports about “resistant
superbugs” appeared in the news. While reasons for this resistance development are easily …

Vibrio cholerae can switch between motile and biofilm lifestyles. The last decades have
been marked by a remarkable increase in our knowledge of the structure, regulation, and …

To cause the diarrheal disease cholera, Vibrio cholerae must effectively colonize the small
intestine. In order to do so, the bacterium needs to successfully travel through the stomach …

A type VI secretion system (T6SS) was recently shown to be required for full virulence of
Vibrio cholerae O37 serogroup strain V52. In this study, we systematically mutagenized …

Outer membrane vesicles (OMVs) produced by Gram-negative bacteria provide an
interesting research material for defining cell-envelope proteins without experimental cell …

In many bacteria, including Vibrio cholerae, cyclic dimeric guanosine monophosphate (c-di-
GMP) controls the motile to biofilm life style switch. Yet, little is known about how this occurs …