[HTML][HTML] Polymicrobial infections and biofilms: clinical significance and eradication strategies

VT Anju, S Busi, M Imchen, R Kumavath, MS Mohan… - Antibiotics, 2022 - mdpi.com
Biofilms are population of cells growing in a coordinated manner and exhibiting resistance
towards hostile environments. The infections associated with biofilms are difficult to control …

Pseudomonas aeruginosa biofilms and their partners in crime

MM Cendra Gascón… - Biotechnology …, 2021 - upcommons.upc.edu
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact
with a broad range of microorganisms have a substantial clinical impact. This review focuses …

Pseudomonas aeruginosa biofilm exopolysaccharides: assembly, function, and degradation

AA Gheorghita, DJ Wozniak, MR Parsek… - FEMS Microbiology …, 2023 - academic.oup.com
The biofilm matrix is a fortress; sheltering bacteria in a protective and nourishing barrier that
allows for growth and adaptation to various surroundings. A variety of different components …

“It takes a village”: mechanisms underlying antimicrobial recalcitrance of polymicrobial biofilms

G Orazi, GA O'Toole - Journal of Bacteriology, 2019 - journals.asm.org
Chronic infections are frequently caused by polymicrobial biofilms. Importantly, these
infections are often difficult to treat effectively in part due to the recalcitrance of biofilms to …

Triple threat: how diabetes results in worsened bacterial infections

BP Darwitz, CJ Genito, LR Thurlow - Infection and Immunity, 2024 - journals.asm.org
Diabetes mellitus, characterized by impaired insulin signaling, is associated with increased
incidence and severity of infections. Various diabetes-related complications contribute to …

Bacterial community interactions during chronic respiratory disease

AL Welp, JM Bomberger - Frontiers in cellular and infection …, 2020 - frontiersin.org
Chronic respiratory diseases including chronic rhinosinusitis, otitis media, asthma, cystic
fibrosis, non-CF bronchiectasis, and chronic obstructive pulmonary disease are a major …

Pseudomonas aeruginosa Alters Staphylococcus aureus Sensitivity to Vancomycin in a Biofilm Model of Cystic Fibrosis Infection

G Orazi, GA O'Toole - MBio, 2017 - journals.asm.org
The airways of cystic fibrosis (CF) patients have thick mucus, which fosters chronic,
polymicrobial infections. Pseudomonas aeruginosa and Staphylococcus aureus are two of …

Salmonella Biofilm Formation, Chronic Infection, and Immunity Within the Intestine and Hepatobiliary Tract

JE Harrell, MM Hahn, SJ D'Souza… - Frontiers in cellular …, 2021 - frontiersin.org
Within the species of Salmonella enterica, there is significant diversity represented among
the numerous subspecies and serovars. Collectively, these account for microbes with …

Pseudomonas aeruginosa exoproducts determine antibiotic efficacy against Staphylococcus aureus

L Radlinski, SE Rowe, LB Kartchner, R Maile… - PLoS …, 2017 - journals.plos.org
Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently
fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality …

Interaction between Staphylococcus aureus and Pseudomonas aeruginosa is beneficial for colonisation and pathogenicity in a mixed biofilm

PM Alves, E Al-Badi, C Withycombe… - Pathogens and …, 2018 - academic.oup.com
Debate regarding the co-existence of Staphylococcus aureus and Pseudomonas
aeruginosa in wounds remains contentious, with the dominant hypothesis describing a …