Transforming growth factor-β (TGFβ) signalling controls multiple cell fate decisions during
development and tissue homeostasis; hence, dysregulation of this pathway can drive …

Glioma is the most common intracranial primary malignancy, with limited treatment options
and a poor overall survival (OS). Immunotherapy has been used successfully in various …

Immunotherapy holds great promise for patients undergoing tumor treatment. However, the
clinical effect of immunotherapy is limited because of tumor immunogenicity and its …

Half a century after its initial emergence, lanthanide photonics is facing a profound
remodeling induced by the upsurge of nanomaterials. Lanthanide‐doped nanomaterials …

Optogenetic is a technique that combines optics and genetics to control specific neurons.
This technique usually uses adenoviruses that encode photosensitive protein. The …

Cells generate and sense mechanical forces that trigger biochemical signals to elicit cellular
responses that control cell fate changes. Mechanical forces also physically distort …

The clinical outcomes of programmed cell death protein‐1 (PD‐1)/programmed death ligand‐
1 (PD‐L1) blockade are usually limited by the multiple immune evasion mechanism of the …

Malignant melanoma is one of the most common tumours and has the highest mortality rate
of all types of skin cancers worldwide. Traditional and novel therapeutic approaches …

The old Greek aphorism 'Panta Rhei'('everything flows') is true for all living things in general.
As a dynamic process, calcium signaling plays fundamental roles in cellular activities under …

By offering the possibility to manipulate cellular functions with spatiotemporal control,
optogenetics represents an attractive tool for dissecting immune responses. However …